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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Nov 27, 2024; 16(11): 1282-1289
Published online Nov 27, 2024. doi: 10.4254/wjh.v16.i11.1282
Published online Nov 27, 2024. doi: 10.4254/wjh.v16.i11.1282
Overexpression of proteasome 26S subunit non-ATPase 6 protein and its clinicopathological significance in intrahepatic cholangiocarcinoma
Zhong-Qing Tang, Department of Pathology, Wuzhou Gongren Hospital/The Seventh Affiliated Hospital of Guangxi Medical University, Wuzhou 543000, Guangxi Zhuang Autonomous Region, China
Yu-Lu Tang, Kai Qin, Qi Li, Gang Chen, Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Yu-Bin Huang, Jian-Jun Li, Department of General Surgery, The Second Affiliated Hospital of Guangxi Medical University, Nanning 530007, Guangxi Zhuang Autonomous Region, China
Co-first authors: Zhong-Qing Tang and Yu-Lu Tang.
Author contributions: Tang ZQ, Tang YL, and Li JJ conceived and designed the study; Qin K analyzed the data and prepared all the graphs; Li Q, Chen G, and Huang YB provided technical support and experimental materials; Tang ZQ and Tang YL drafted the manuscript; Li JJ revised the manuscript. The decision for co-first authorship is based on the substantial and equal contributions of Tang ZQ and Tang YL to the conception, design, execution, and interpretation of the research presented in this manuscript. Both authors have played a crucial role in drafting and revising the manuscript and have approved the final version. Both authors actively participated in the preparation of the manuscript and are equally accountable for its content.
Institutional review board statement: The protocol for this research project has been approved by a suitably constituted Ethics Committee of the institution Committee of Pantomics, Inc. [Approval No. Fanpu(2018)23].
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that there are no financial conflicts of interest to disclose.
Data sharing statement: The data that support the findings of this study are available from the corresponding author at lijianjunmail@163.com upon reasonable request.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Jun Li, PhD, Surgeon, Department of General Surgery, The Second Affiliated Hospital of Guangxi Medical University, No. 166 East University Road, Xixiangtang District, Nanning 530007, Guangxi Zhuang Autonomous Region, China.
Received: May 25, 2024
Revised: June 23, 2024
Accepted: July 23, 2024
Published online: November 27, 2024
Processing time: 164 Days and 19.8 Hours
Revised: June 23, 2024
Accepted: July 23, 2024
Published online: November 27, 2024
Processing time: 164 Days and 19.8 Hours
Core Tip
Core Tip: This study examined the expression and clinicopathological significance of proteasome 26S subunit non-ATPase 6 (PSMD6) in intrahepatic cholangiocarcinoma (ICC). It was discovered that the PSMD6 gene was essential for the prolife