Review
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jun 27, 2023; 15(6): 741-754
Published online Jun 27, 2023. doi: 10.4254/wjh.v15.i6.741
Recent advances in pathophysiology, diagnosis and management of hepatorenal syndrome: A review
Calvin Kiani, Andreas G Zori
Calvin Kiani, Andreas G Zori, Department of Internal Medicine, Section of Gastroenterology and Hepatology, University of Florida, Gainesville, FL 32610, United States
Author contributions: Kiani C drafted the initial manuscript; Zori AG contributed to, edited, and drafted the final manuscript.
Conflict-of-interest statement: Andreas G Zori and Calvin Kiani have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Andreas G Zori, MD, Assistant Professor, Department of Internal Medicine, Section of Gastroenterology and Hepatology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, United States. andreas.zori@medicine.ufl.edu
Received: February 28, 2023
Peer-review started: February 28, 2023
First decision: March 10, 2023
Revised: April 18, 2023
Accepted: May 6, 2023
Article in press: May 6, 2023
Published online: June 27, 2023
Processing time: 117 Days and 12.6 Hours
Core Tip

Core Tip: Hepatorenal syndrome (HRS) is a specific form of acute kidney injury that occurs in the presence of severe acute liver injury (e.g., acute liver failure or severe alcoholic hepatitis), decompensated cirrhosis, or acute on chronic liver failure and is particularly associated with poor prognosis. Here, we reviewed some of the recent advancements in the diagnosis and treatment of HRS.