Liver steatosis in patients with rheumatoid arthritis treated with methotrexate is associated with body mass index
Agustin Castiella, Department of Gastroenterology Service, Donostia University Hospital, Donostia 20014, Spain
Luis Lopez-Dominguez, Andrea De Diego, Joaquin Belzunegui, Department of Rheumatology, Donostia University Hospital, Donostia 20014, Spain
Maria J Sanchez-Iturri, Eva Zapata, Department of Gastroenterology, Donostia University Hospital, Donostia 20014, Spain
Iratxe Urreta, Department of Clinical Epidemiology, Donostia University Hospital, Donostia 20014, Spain
Author contributions: Castiella A and Lopez-Dominguez L were the guarantors and designed the study; Castiella A, Lopez-Dominguez L, Sanchez-Iturri MJ, Urreta I, De Diego A, Belzunegui J, and Zapata E participated in the acquisition, analysis, and interpretation of the data and drafted the initial manuscript; Castiella A, Lopez-Dominguez L, and Zapata E revised the article critically for important intellectual content.
Institutional review board statement: Institutional review board statement statement: The study was reviewed and approved by the clinical research ethics committee of the Gipuzkoa health area (Código de Protocolo: ACLFSC-2018-01; Acta 01/2019).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors report having no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement checklist of items, and the manuscript was prepared and revised according to the STROBE Statement checklist of items.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Agustin Castiella, MD, PhD, Staff Physician, Department of Gastroenterology Service, Donostia University Hospital, Servicio Digestivo, Donostia 20014, Spain. email@example.com
Received: December 16, 2022
Peer-review started: December 16, 2022
First decision: December 31, 2022
Revised: January 7, 2023
Accepted: April 10, 2023
Article in press: April 10, 2023
Published online: May 27, 2023