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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Aug 27, 2022; 14(8): 1550-1561
Published online Aug 27, 2022. doi: 10.4254/wjh.v14.i8.1550
Published online Aug 27, 2022. doi: 10.4254/wjh.v14.i8.1550
Outcomes of patients with post-hepatectomy hypophosphatemia: A narrative review
Kai Siang Chan, Vishal G Shelat, Department of General Surgery, Tan Tock Seng Hospital, Singapore 308433, Singapore
Swetha Mohan, Vishal G Shelat, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore
Author contributions: Chan KS and Mohan S acquired the data, prepared the tables, drafted the article and approved the final version of the manuscript to be published; Chan KS interpreted and analysed the data and prepared the figures; Shelat VG conceptualized and designed the study and made critical revision of the manuscript and approved the final version of the manuscript to be published.
Conflict-of-interest statement: All authors declare no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai Siang Chan, MBBS, Doctor, Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore. kchan023@e.ntu.edu.sg
Received: April 16, 2022
Peer-review started: April 16, 2022
First decision: May 31, 2022
Revised: May 31, 2022
Accepted: August 1, 2022
Article in press: August 1, 2022
Published online: August 27, 2022
Peer-review started: April 16, 2022
First decision: May 31, 2022
Revised: May 31, 2022
Accepted: August 1, 2022
Article in press: August 1, 2022
Published online: August 27, 2022
Core Tip
Core Tip: Hypophosphatemia (HP) is a clinical spectrum which range from asymptomatic to severe complications such as neuromuscular and pulmonary complications, or even death. Post-hepatectomy HP (PHH) has been reported to be 55.5%-100%. Pathophysiologic mechanisms have been proposed. However, literature on the outcomes of patients following PHH is scarce. This is the first review to summarize existing literature on the pathophysiology of PHH in both healthy and diseased liver, and its impact on post-operative outcomes.