Case Control Study
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World J Hepatol. Jun 27, 2022; 14(6): 1142-1149
Published online Jun 27, 2022. doi: 10.4254/wjh.v14.i6.1142
Clinical outcomes of coronavirus disease 2019 in liver transplant recipients
Muhammad Shafiq, Cheryl Gibson
Muhammad Shafiq, Cheryl Gibson, Department of General and Geriatric Medicine, University of Kansas Medical Center, Kansas City, KS 66160, United States
Author contributions: Shafiq M was involved in all aspects of this study, including but not limited to study design, data collection, data analyses, and writing of the abstract and manuscript; Gibson C assisted with the study design and data analyses.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of University of Kansas Medical Center (Kansas City, KS, United States).
Informed consent statement: In accordance with the retrospective design of the study, based upon chart reviews, no informed consent was required.
Conflict-of-interest statement: All the authors have no conflicts of interest to declare.
Data sharing statement: All relevant data has been provided in this article. No additional data is available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Muhammad Shafiq, MD, Assistant Professor, Department of General and Geriatric Medicine, University of Kansas Medical Center, 4000 Cambridge Street, 6040 Delp & Mail Stop 1020, Kansas City, KS 66160, United States. mshafiq@kumc.edu
Received: January 5, 2022
Peer-review started: January 5, 2022
First decision: March 7, 2022
Revised: April 7, 2022
Accepted: May 28, 2022
Article in press: May 28, 2022
Published online: June 27, 2022
Processing time: 168 Days and 19.8 Hours
Core Tip

Core Tip: This was a case-control study that assessed the clinical outcomes of coronavirus disease 2019 (COVID-19) in liver transplant recipients. Our study did not show a significant difference in death or hospitalization rate due to COVID-19 between patients who had liver transplantation and those who did not. Our study also did not find any difference between these two groups in terms of duration of hospital stay, need for supplemental oxygen, presence of at least one type of end-organ damage, effect on liver enzymes, and d-dimer levels. Therefore, COVID-19 should not impact timely health care access and immunosuppression continuation among liver transplant recipients.