Garrido I, Andrade P, Pacheco J, Rios E, Macedo G. Not all liver tumors are alike — an accidentally discovered primary hepatic leiomyosarcoma: A case report. World J Hepatol 2022; 14(4): 860-865 [PMID: 35646269 DOI: 10.4254/wjh.v14.i4.860]
Corresponding Author of This Article
Isabel Garrido, MD, Doctor, Gastroenterology and Hepatology Department, Centro Hospitalar Universitário de São João, Alameda Prof. Hernâni Monteiro, Porto 4200-319, Portugal. isabelmng@hotmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Apr 27, 2022; 14(4): 860-865 Published online Apr 27, 2022. doi: 10.4254/wjh.v14.i4.860
Not all liver tumors are alike — an accidentally discovered primary hepatic leiomyosarcoma: A case report
Isabel Garrido, Patrícia Andrade, João Pacheco, Elisabete Rios, Guilherme Macedo
Isabel Garrido, Patrícia Andrade, Guilherme Macedo, Gastroenterology and Hepatology Department, Centro Hospitalar Universitário de São João, Porto 4200-319, Portugal
Isabel Garrido, Patrícia Andrade, Guilherme Macedo, World Gastroenterology Organization Porto Training Center, Porto 4200-319, Portugal
João Pacheco, Elisabete Rios, Pathology Department, Centro Hospitalar Universitário de São João, Porto 4200-319, Portugal
Author contributions: Garrido I drafted the manuscript; Garrido I, Andrade P, Pacheco J, Rios E and Macedo G have revised and finalized the manuscript; All authors have approved the final version of the manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors have no disclosures to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Isabel Garrido, MD, Doctor, Gastroenterology and Hepatology Department, Centro Hospitalar Universitário de São João, Alameda Prof. Hernâni Monteiro, Porto 4200-319, Portugal. isabelmng@hotmail.com
Received: January 10, 2022 Peer-review started: January 10, 2022 First decision: January 22, 2022 Revised: January 22, 2022 Accepted: March 6, 2022 Article in press: March 6, 2022 Published online: April 27, 2022 Processing time: 101 Days and 11.8 Hours
Core Tip
Core Tip: Sarcomas comprise only 1%-2% of all primary liver malignancies, and leiomyosarcoma is even rarer. We report a rare case of primary hepatic leiomyosarcoma accidentally diagnosed and surgically treated. The diagnosis requires a high level of suspicion because the clinical scenario and cross-imaging are not specific. Thus, histological examination is the only way to reach the diagnosis. In our case, the tumor probably originated from the left branch of the portal vein or the round ligament. Radical hepatectomy is the cornerstone of treatment. However, this tumor has aggressive metastatic potential and is usually diagnosed in locally advanced or metastatic disease. Two years after surgical resection, our patient is alive and with no evidence of tumor recurrence, likely because the diagnosis was established at an early stage and the surgery achieved a tumor-free margin.