Pediatric liver transplantation outcomes from a single center in Thailand

doi:10.4254/wjh.v14.i3.583

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Mar 27, 2022 (publication date) through May 5, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Hepatol. Mar 27, 2022; 14(3): 583-591
Published online Mar 27, 2022. doi: 10.4254/wjh.v14.i3.583

Pediatric liver transplantation outcomes from a single center in Thailand

Sittichoke Prachuapthunyachart, Palittiya Sintusek, Chomchanat Tubjareon, Nataruks Chaijitraruch, Anapat Sanpavat, Teerasak Phewplung, Piyaporn Wanawongsawad, Ai-lada Intrarakamhang, Voranush Chongsrisawat

Sittichoke Prachuapthunyachart, Palittiya Sintusek, Chomchanat Tubjareon, Voranush Chongsrisawat, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand

Palittiya Sintusek, Thai Pediatric Gastroenterology, Hepatology and Immunology Research Unit, Department of Pediatrics, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross, Chulalongkorn University, Bangkok 10330, Thailand

Nataruks Chaijitraruch, Piyaporn Wanawongsawad, Ai-lada Intrarakamhang, Excellence Center of Organ Transplantation, King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand

Anapat Sanpavat, Department of Pathology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand

Teerasak Phewplung, Department of Radiology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand

Author contributions: Prachuapthunyachart S designed the study, drafted the initial manuscript, collected, interpreted and analyzed the data; Sintusek P, Tubjareon C, Chaijitraruch N, Sanpavat A, and Phewplung T revised the article critically for important intellectual content; Wanawongsawad P and Intrarakamhang A collected the data; Chongsrisawat V provided valuable advice and revised the article critically for important intellectual content; All authors read and approved the final manuscript.

Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (IRB approval number: 322/64).

Informed consent statement: The informed consent was waived for the study as approved by the IRB.

Conflict-of-interest statement: There are no conflicts of interest to report.

Data sharing statement: No additional data are available.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Voranush Chongsrisawat, MD, Associate Professor, Doctor, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, 1873, Rama 4 Road, Pathumwan, Bangkok 10330, Thailand. voranush.c@chula.ac.th

Received: August 1, 2021
Peer-review started: August 1, 2021
First decision: September 29, 2021
Revised: October 31, 2021
Accepted: February 19, 2022
Article in press: February 19, 2022
Published online: March 27, 2022

Core Tip

Core Tip: Pediatric liver transplantation (LT) is an acceptable life-saving operation for several chronic liver diseases and irreversible acute liver failure. This single-center data was analyzed from pediatric LTs performed between August 2004 and November 2019. This study evaluated the most extensive series of pediatric liver transplant recipients in Thailand in the past two decades. Preoperative and postoperative data, including complications and survival, were reviewed. The overall 5-year survival rate was > 90%. In addition, the satisfying outcomes of ABO-incompatible living-donor and hepatitis B core antibody-positive graft transplantation were also highlighted.