Retrospective Cohort Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Oct 27, 2022; 14(10): 1899-1906
Published online Oct 27, 2022. doi: 10.4254/wjh.v14.i10.1899
Quality of life, depression and anxiety in potential living liver donors for pediatric recipients: A retrospective single center experience
Paula K Reine, Flavia Feier, Eduardo Antunes da Fonseca, Rosely G Hernandes, Joao Seda-Neto
Paula K Reine, Rosely G Hernandes, Department of Psychology, Hospital Sírio-Libanês, São Paulo 01308901, Brazil
Flavia Feier, Department ofLiver Transplantation, Santa Casa de Porto Alegre, Porto Alegre 90020090, Brazil
Eduardo Antunes da Fonseca, Joao Seda-Neto, Department of Liver Transplantation, Hospital Sírio-Libanês, São Paulo 01308901, Brazil
Author contributions: Reine PK contributed to study design, data collection, manuscript writing; Feier F contributed to data analysis, manuscript writing; Hernandes RG contributed to data collection, manuscript final version critical analysis; da Fonseca EA contributed to manuscript writing, manuscript final version critical analysis; Seda-Neto J contributed to study design, manuscript writing, data analysis.
Institutional review board statement: The study was reviewed and approved for publication by our Institutional Reviewer.
Informed consent statement: It was exempted because of the retrospective nature of the study by the Hospital’s Ethics Committee.
Conflict-of-interest statement: None of the authors have any conflicts of interest related to the manuscript.
Data sharing statement: The original anonymous dataset is available upon request from the corresponding author at
STROBE statement: The authors have read the STROBE statement, and the manuscript was prepared and revised according to the STROBE statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Joao Seda-Neto, PhD, Surgeon, Department of Liver Transplantation, Hospital Sírio-Libanês, Rua Adma Jafet, 91, São Paulo 01308901, Brazil.
Received: June 6, 2022
Peer-review started: June 6, 2022
First decision: July 12, 2022
Revised: August 21, 2022
Accepted: September 21, 2022
Article in press: September 21, 2022
Published online: October 27, 2022
Core Tip

Core Tip: The role of a pre-donation sociopsychological evaluation of a donor candidate is as important to the success of the procedure as is the medical assessment. This implies recovery from the operation and prompt engagement in pre-transplant professional and social activities without leading to psychological or physical distress. The present study evaluates socio-demographics and psychological aspects of potential living liver donors for pediatric liver transplantation in a cohort of 250 patients. It also investigates specific questions regarding donation, decision-making processes, and feelings of ambivalence.