de Jesus RP, de Carvalho JF, de Oliveira LPM, Cunha CM, Alves TCHS, Vieira STB, Figueiredo VM, Bueno AA. Metabolic and nutritional triggers associated with increased risk of liver complications in SARS-CoV-2. World J Hepatol 2022; 14(1): 80-97 [PMID: 35126841 DOI: 10.4254/wjh.v14.i1.80]
Corresponding Author of This Article
Jozélio Freire de Carvalho, MD, PhD, Adjunct Professor, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon, s/n - Canela, Salvador 40231-300, Bahia, Brazil. jotafc@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Jan 27, 2022; 14(1): 80-97 Published online Jan 27, 2022. doi: 10.4254/wjh.v14.i1.80
Metabolic and nutritional triggers associated with increased risk of liver complications in SARS-CoV-2
Rosangela Passos de Jesus, Jozélio Freire de Carvalho, Lucivalda Pereira Magalhães de Oliveira, Carla de Magalhães Cunha, Thaisy Cristina Honorato Santos Alves, Sandra Tavares Brito Vieira, Virginia Maria Figueiredo, Allain Amador Bueno
Rosangela Passos de Jesus, Lucivalda Pereira Magalhães de Oliveira, Carla de Magalhães Cunha, Thaisy Cristina Honorato Santos Alves, Sandra Tavares Brito Vieira, Postgraduate Program in Food, Nutrition and Health at the School of Nutrition of the Federal University of Bahia, Salvador 40.110-150, Bahia, Brazil
Jozélio Freire de Carvalho, Institute of Health Sciences, Federal University of Bahia, Salvador 40231-300, Bahia, Brazil
Thaisy Cristina Honorato Santos Alves, Institute of Life Sciences, State University of Bahia, Salvador 41.150-000, Bahia, Brazil
Virginia Maria Figueiredo, Department of Gastroenterology, IPEMED, Ipemed Faculty of Medical Sciences, Salvador 40170-110, Bahia, Brazil
Allain Amador Bueno, College of Health, Life and Environmental Sciences, University of Worcester, Worcester WR2 6AJ, United Kingdom
Author contributions: All authors have contributed to conceptualization, literature appraisal, data gathering and original draft preparation; de Jesus RP, de Carvalho JF, Figueiredo VM and Bueno AA contributed to the final considerations, conclusions and final version of the manuscript; all authors have read and agreed to the published version of the manuscript.
Conflict-of-interest statement: The authors declare that this research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jozélio Freire de Carvalho, MD, PhD, Adjunct Professor, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon, s/n - Canela, Salvador 40231-300, Bahia, Brazil. jotafc@gmail.com
Received: May 13, 2021 Peer-review started: May 13, 2021 First decision: July 18, 2021 Revised: July 28, 2021 Accepted: December 22, 2022 Article in press: December 22, 2021 Published online: January 27, 2022 Processing time: 253 Days and 7.2 Hours
Core Tip
Core Tip: Coronavirus disease-associated liver injury may occur in the progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with or without pre-existing liver disease. Patients with cirrhosis-associated immune dysfunction are particularly vulnerable. Strategies for management of sepsis and SARS are suggested in SARS-CoV-2 for intensive care patients, including early enteral nutrition soon after intensive care unit admission. Transition to parenteral nutrition should not be delayed when energy and protein targets cannot be met via EN. In outpatient settings, micronutrient and ω-3 fatty acids have shown beneficial effects upon immune function and inflammation modulation and may be beneficial in management for SARS-CoV-2 liver patients.
