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World J Hepatol. Sep 27, 2021; 13(9): 1079-1097
Published online Sep 27, 2021. doi: 10.4254/wjh.v13.i9.1079
Indeterminate liver lesions on gadoxetic acid-enhanced magnetic resonance imaging of the liver: Case-based radiologic-pathologic review
Jurate Noreikaite, Dekan Albasha, Vijay Chidambaram, Ankur Arora, Ashok Katti
Jurate Noreikaite, Dekan Albasha, Vijay Chidambaram, Ankur Arora, Ashok Katti, Department of Radiology, Liverpool University Hospitals NHS Foundation Trust, Liverpool L7 8XP, United Kingdom
Author contributions: Noreikaite J performed the majority of the writing, literature review and analysis and prepared the figures; Albasha D contributed with design of study, literature review and drafting; Chidambaram V, Arora A and Katti A contributed to this paper with critical revision, editing and final approval of the final revision; Katti A has also provided majority of the case examples; all authors have read and approve the final manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jurate Noreikaite, MD, Doctor, Department of Radiology, Liverpool University Hospitals NHS Foundation Trust, Prescot Street, Liverpool L7 8XP, United Kingdom. jurate.noreikaite@liverpoolft.nhs.uk
Received: February 24, 2021
Peer-review started: February 24, 2021
First decision: June 4, 2021
Revised: June 24, 2021
Accepted: August 6, 2021
Article in press: August 6, 2021
Published online: September 27, 2021
Processing time: 209 Days and 19.8 Hours
Core Tip

Core Tip: Being familiar with the typical magnetic resonance imaging aspects of focal liver lesions as well as knowing the uncommon and overlapping imaging features can help reach an accurate diagnosis without the need for further interventions. Gadoxetic acid has been shown to significantly increase diagnostic accuracy in the detection and characterization of liver abnormalities, although in certain challenging cases it may be prudent to seek histological confirmation.