Copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. May 27, 2021; 13(5): 533-542
Published online May 27, 2021. doi: 10.4254/wjh.v13.i5.533
Published online May 27, 2021. doi: 10.4254/wjh.v13.i5.533
Direct, remote and combined ischemic conditioning in liver surgery
Rafał Stankiewicz, Michał Grąt, Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw 02-097, Poland
Author contributions: Stankiewicz R conceptualized the study, did the literature search, wrote the paper and approved the final version of the article; Grąt M conceptualized the study, did the literature search, critically reviewed the paper and approved the final version of the article.
Supported by National Science Centre , Poland, No. 2019/34/E/NZ5/00433.
Conflict-of-interest statement: Grąt M reports grants from the National Science Centre, Poland during the conduct of the study; Stankiewicz R has none to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rafał Stankiewicz, MD, PhD, Surgeon, Department of General, Transplant and Liver Surgery, Medical University of Warsaw, 1A Banacha Street, Warsaw 02-097, Poland. rstankiewicz0@gmail.com
Received: February 17, 2021
Peer-review started: February 17, 2021
First decision: March 16, 2021
Revised: March 28, 2021
Accepted: May 7, 2021
Article in press: May 7, 2021
Published online: May 27, 2021
Peer-review started: February 17, 2021
First decision: March 16, 2021
Revised: March 28, 2021
Accepted: May 7, 2021
Article in press: May 7, 2021
Published online: May 27, 2021
Core Tip
Core Tip: The concept of ischemic conditioning seems easy to apply and is an inexpensive method with the potential to protect the liver during hepatic surgery. It covers a wide spectrum of techniques and allows adjustment of the method to the particular patient. Unfortunately, despite promising animal studies in preventing ischemia-reperfusion injury by ischemic conditioning, currently there is a lack of sufficient data on its clinical efficacy in humans.