Abnormal liver enzymes: A review for clinicians

doi:10.4254/wjh.v13.i11.1688

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Nov 27, 2021 (publication date) through Dec 28, 2024

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World Journal of Hepatology

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1948-5182

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World J Hepatol. Nov 27, 2021; 13(11): 1688-1698
Published online Nov 27, 2021. doi: 10.4254/wjh.v13.i11.1688

Abnormal liver enzymes: A review for clinicians

M Ammar Kalas, Luis Chavez, Monica Leon, Pahnwat Tonya Taweesedt, Salim Surani

M Ammar Kalas, Luis Chavez, Department of Internal Medicine, Texas Tech University Health Science Center, El Paso, TX 79905, United States

Monica Leon, Department of General Surgery, University of Mexico, Ciudad de Mexico 01120, Mexico

Pahnwat Tonya Taweesedt, Department of Medicine, Corpus Christi Medical Center, Corpus Christi, TX 78412, United States

Salim Surani, Department of Medicine, Texas A&M University, College Station, TX 77843, United States

Salim Surani, Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, United States

Author contributions: All authors have contributed to the preparation and review of the manuscript.

Conflict-of-interest statement: The authors have no conflict of interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Salim Surani, FACP, FCCP, MD, MSc, Doctor, Professor, Medicine, Texas A&M University, 400 Bizzell St, College Station, TX 77843, United States. srsurani@hotmail.com

Received: May 15, 2021
Peer-review started: May 15, 2021
First decision: July 8, 2021
Revised: July 24, 2021
Accepted: August 23, 2021
Article in press: August 23, 2021
Published online: November 27, 2021
Processing time: 193 Days and 6.5 Hours

Core Tip

Core Tip: Liver function test are one of the most commonly ordered tests. With the automation of test and its inclusion in the complete metabolic profile, the knowledge as it pertains to its interpretation is of paramount importance. It is also important for the clinician to understand the difference between cholestatic and hepatocellular abnormalities. This can be of help for the clinician to formulate appropriate further diagnostic workup and plan the treatment.