Successful treatment of noncirrhotic portal hypertension with eculizumab in paroxysmal nocturnal hemoglobinuria: A case report
Alexandra Alexopoulou, Iliana Mani, Flora Kontopidou, Ioanna Tsironi, Marina Noutsou, Helen Pantelidaki, Spyros P Dourakis, 2nd Department of Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens 11527, Greece
Dina G Tiniakos, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle NE2 4HH, United Kingdom
Dina G Tiniakos, Department of Pathology, Aretaieion Hospital, National and Kapodistrian University of Athens, Athens 11528, Greece
Author contributions: Alexopoulou A and Mani I reviewed the literature and contributed to manuscript drafting; Tiniakos DG analyzed and interpreted the histological findings and contributed to manuscript drafting; Kontopidou F performed the hematological consultation and contributed to manuscript drafting; Pantelidaki H, Noutsou M, and Tsironi I reviewed the literature and contributed to manuscript drafting; Dourakis SP was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2013), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Alexandra Alexopoulou, MD, PhD, Associate Professor, 2nd Department of Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital, 114 Vas Sophias St, Athens 11527, Greece. email@example.com
Telephone: +30-213-2088178 Fax: +30-210-7706871
Received: March 6, 2019
Peer-review started: March 7, 2019
First decision: April 11, 2019
Revised: April 25, 2019
Accepted: May 20, 2019
Article in press: May 20, 2019
Published online: May 27, 2019