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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Sep 27, 2018; 10(9): 637-638
Published online Sep 27, 2018. doi: 10.4254/wjh.v10.i9.637
Published online Sep 27, 2018. doi: 10.4254/wjh.v10.i9.637
Protecting kidneys in liver transplant patients: A pathway to preventive interventions
Lena Sibulesky, Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, WA 98195, United States
Scott W Biggins, Division of Gastroenterology and Hepatology, Department of Medicine, University of Washington, Seattle, WA 98195, United States
Raimund Pichler, Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA 98195, United States
Author contributions: Sibulesky L, Biggins SW and Pichler R wrote this letter.
Conflict-of-interest statement: There are no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Lena Sibulesky, MD, Associate Professor, Surgeon, Division of Transplant Surgery, Department of Surgery, University of Washington, 1959 NE Pacific Street, Box 356410, Seattle, WA 98195, United States. lenasi@uw.edu
Telephone: +1-206-5987797 Fax: +1-206-5984287
Received: May 16, 2018
Peer-review started: May 16, 2018
First decision: May 24, 2018
Revised: May 30, 2018
Accepted: June 28, 2018
Article in press: June 28, 2018
Published online: September 27, 2018
Processing time: 134 Days and 15.1 Hours
Peer-review started: May 16, 2018
First decision: May 24, 2018
Revised: May 30, 2018
Accepted: June 28, 2018
Article in press: June 28, 2018
Published online: September 27, 2018
Processing time: 134 Days and 15.1 Hours
Core Tip
Core tip: Acute kidney injury early post liver transplantation is a major cause of morbidity and mortality. The etiology is multifactorial. The renal hypoperfusion and hepatic ischemia-reperfusion injury are being increasingly recognized. Further studies need to focus on therapies that would attenuate this injury.