Copyright
©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 27, 2018; 10(12): 907-910
Published online Dec 27, 2018. doi: 10.4254/wjh.v10.i12.907
Published online Dec 27, 2018. doi: 10.4254/wjh.v10.i12.907
Stem cell transplantation for the treatment of end-stage liver disease
Dong-Bo Wu, En-Qiang Chen, Hong Tang, Center of Infectious Diseases, West China Hospital of Sichuan University, Sichuan 610041, Chengdu Province, China
Author contributions: Chen EQ and Tang H designed the structure of this paper. Wu DB searched the literature and wrote the paper; Chen EQ critically revised the paper.
Conflict-of-interest statement: No potential conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: En-Qiang Chen, MD, PhD, Associate Professor, Doctor, Center of Infectious Diseases, West China Hospital of Sichuan University, No.37 Guo Xue Xiang, Wuhou District, Chengdu 610041, Sichuan Province, China. chenenqiang@scu.edu.cn
Telephone: +86-28-85422859 Fax: +86-28-85423056
Received: July 6, 2018
Peer-review started: July 6, 2018
First decision: August 8, 2018
Revised: August 14, 2018
Accepted: October 8, 2018
Article in press: October 9, 2018
Published online: December 27, 2018
Processing time: 174 Days and 2.3 Hours
Peer-review started: July 6, 2018
First decision: August 8, 2018
Revised: August 14, 2018
Accepted: October 8, 2018
Article in press: October 9, 2018
Published online: December 27, 2018
Processing time: 174 Days and 2.3 Hours
Core Tip
Core tip: Stem cells have the capacity for multiple rounds of self-renewal and differentiation, and play important roles in numerous biological functions. Treatment of end-stage liver disease via stem cell transplantation has emerged as an effective therapeutic alternative in clinical practice. However, caution should be paid to ensuring the safety and efficacy of stem cell transplantation to avoid the use of products that are not rigorously tested that may put patients at risk.