Prospective Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jan 27, 2018; 10(1): 134-141
Published online Jan 27, 2018. doi: 10.4254/wjh.v10.i1.134
Effect of transplant center volume on post-transplant survival in patients listed for simultaneous liver and kidney transplantation
Rohan M Modi, Dmitry Tumin, Andrew J Kruger, Eliza W Beal, Don Hayes Jr, James Hanje, Anthony J Michaels, Kenneth Washburn, Lanla F Conteh, Sylvester M Black, Khalid Mumtaz
Rohan M Modi, Andrew J Kruger, Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Dmitry Tumin, Department of Anesthesiology and Pain Medicine, Nationwide Children’s Hospital, Columbus, OH 43205, United States
Eliza W Beal, Kenneth Washburn, Sylvester M Black, Department of General Surgery, Division of Transplantation, Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Eliza W Beal, Don Hayes Jr, James Hanje, Anthony J Michaels, Kenneth Washburn, Lanla F Conteh, Sylvester M Black, Khalid Mumtaz, Comprehensive Transplant Center, Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Don Hayes Jr, Section of Pulmonary Medicine, Nationwide Children’s Hospital, Columbus, OH 43205, United States
James Hanje, Anthony J Michaels, Lanla F Conteh, Khalid Mumtaz, Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Author contributions: Modi RM, Tumin D, Kruger AJ, Beal EW, Hayes Jr D, Hanje J, Michaels AJ, Washburn K, Conteh LF, Black SM, and Mumtaz K made substantial contributions to the conception, design of the study, acquisition of data, analysis/contribution of data, drafting and critically revising the manuscript; all authors have given final approval of the final version.
Institutional review board statement: The institutional review board at Nationwide Children’s Hospital exempted the study from review (IRB16-01193).
Informed consent statement: Due to the nature of this research, informed consent was not required.
Conflict-of-interest statement: None of the above listed authors have any reported conflicts of interest to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Khalid Mumtaz, MD, MSC, Assistant Professor, Doctor, Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, Ohio State University Wexner Medical Center, 410 W. 10th Ave., North 235 Doan Hall, Columbus, OH 43210, United States. khalid.mumtaz@osumc.edu
Telephone: +1-614-2936255 Fax: +1-614-2938516
Received: September 26, 2017
Peer-review started: October 1, 2017
First decision: November 27, 2017
Revised: December 1, 2017
Accepted: December 13, 2017
Article in press: December 13, 2017
Published online: January 27, 2018
Processing time: 121 Days and 17.9 Hours
Core Tip

Core tip: Simultaneous liver kidney transplantation (SLKT) has doubled from 2002-2013. We studied the effect of transplant center volume on survival outcomes. There was a significant survival disadvantage for liver transplant alone (LTA) vs SLKT in centers performing 30 SLKT over the study period, although this disadvantage was slightly diminished with increasing center SLKT volume. Therefore, centers with higher transplant volume have a lesser mortality difference in LTA compared to SLKT than those centers with smaller volume.