Published online Sep 27, 2022. doi: 10.4254/wjh.v14.i9.1778
Peer-review started: January 12, 2022
First decision: April 16, 2022
Revised: April 30, 2022
Accepted: August 22, 2022
Article in press: August 22, 2022
Published online: September 27, 2022
No preoperative prognostic models specific to hepatocellular carcinoma patients receiving surgical resection have been considered strong and convincing enough for survival prediction.
We previously derived a nomogram but aimed to simplify the score and compare it with other scoring systems.
To develop a simple preoperative score with satisfactory predictive power compared to postoperative scoring systems.
Significant risk factors were identified using a multivariate Cox proportional hazards model. The homogeneity, Harrell’s C-index, and Akaike information criterion of the different scoring systems were compared.
Five risk factors were identified, and patients were divided into three risk groups. The C-index of our preoperative score was 0.617, which is equal to the value of the AJCC 8th edition.
A modified score was established for survival prediction, and patients were divided into risk groups for preoperative treatment planning.
Specific treatment or monitoring plan modifications for each risk group should be studied and potential correlation with survival benefit should be investigated.