Akbulut S, Isik B, Cicek E, Samdanci E, Yilmaz S. Neuroendocrine tumor incidentally detected during living donor hepatectomy: A case report and review of literature. World J Hepatol 2018; 10(10): 780-784 [PMID: 30386471 DOI: 10.4254/wjh.v10.i10.780]
Corresponding Author of This Article
Sami Akbulut, MD, Associate Professor, Department of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Elazig Yolu 10. Km, Malatya 44280, Turkey. akbulutsami@gmail.com
Research Domain of This Article
Transplantation
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Oct 27, 2018; 10(10): 780-784 Published online Oct 27, 2018. doi: 10.4254/wjh.v10.i10.780
Neuroendocrine tumor incidentally detected during living donor hepatectomy: A case report and review of literature
Sami Akbulut, Burak Isik, Egemen Cicek, Emine Samdanci, Sezai Yilmaz
Sami Akbulut, Burak Isik, Sezai Yilmaz, Department of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Malatya 44280, Turkey
Egemen Cicek, Department of Surgery, Inonu University Faculty of Medicine, Malatya 44280, Turkey
Emine Samdanci, Department of Pathology, Inonu University Faculty of Medicine, Malatya 44280, Turkey
Author contributions: Akbulut S, Isik B, and Cicek E designed the report; Akbulut S collected the patient’s clinical data; Samdanci E provided histopathological information; Akbulut S and Yilmaz S analyzed the data and wrote the paper.
Informed consent statement: The patient involved in this study gave his informed written consent prior to study enrollment, authorizing the use and disclosure of his protected health information.
Conflict-of-interest statement: The author declares no potential conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sami Akbulut, MD, Associate Professor, Department of Surgery and Liver Transplant Institute, Inonu University Faculty of Medicine, Elazig Yolu 10. Km, Malatya 44280, Turkey. akbulutsami@gmail.com
Telephone: +90-422-3410660 Fax: +90-422-3410036
Received: May 18, 2018 Peer-review started: May 18, 2018 First decision: June 6, 2018 Revised: June 19, 2018 Accepted: June 27, 2018 Article in press: June 28, 2018 Published online: October 27, 2018 Processing time: 164 Days and 4.7 Hours
ARTICLE HIGHLIGHTS
Case characteristics
We aimed to present two cases in which grade I neuroendocrine tumors were incidentally detected during our twelve-year living donor hepatectomy experience.
Clinical diagnosis
Intraoperative appearance of the lesions of both patients was compatible with benign disease.
Differential diagnosis
Differential diagnosis of the first case included calcified nodule, benign intestinal tumor, and early stage malignant tumor. Differential diagnosis of the second case includes acute appendicitis, mucocele, and carcinoid tumor
Laboratory diagnosis
No abnormal findings were detected in preoperative biochemical blood tests in both living liver donor candidates.
Imaging diagnosis
No abnormal findings were detected in preoperative radiological examinations in both living liver donor candidates.
Pathological diagnosis
The immunohistochemical examinations of the specimens of both patients were reported as grade I neuroendocrine tumor.
Treatment
While a wedge resection with primary intestinal anastomosis was performed in the first case, simple appendectomy was performed in the second case.
Related reports
To our knowledge, no publication other than our study has ever reported unusual findings, such as cancer, detected incidentally during a living donor hepatectomy procedure.
Experiences and lessons
Even if patients undergoing living donor hepatectomy are healthy individuals, the whole abdominal cavity should be gently palpated and all findings recorded after completing laparotomy. Suspected masses or lesions should be confirmed by frozen section examination.
