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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 18, 2015; 7(29): 2890-2895
Published online Dec 18, 2015. doi: 10.4254/wjh.v7.i29.2890
Management of biliary complications after liver transplantation
Riccardo Memeo, Tullio Piardi, Federico Sangiuolo, Daniele Sommacale, Patrick Pessaux
Riccardo Memeo, Federico Sangiuolo, Patrick Pessaux, Hepato-Biliary and Pancreatic Surgical Unit, General, Digestive and Endocrine Surgery, IRCAD, IHU Mix-Surg, Institute for Minimally Invasive Image-Guided Surgery, University of Strasbourg, 1 place de l’Hôpital, 67091 Strasbourg, France
Tullio Piardi, Daniele Sommacale, Department of General, Digestive and Endocrine Surgery, Hôpital Robert Debré, Centre Hospitalier Universitaire de Reims, Université de Reims Champagne-Ardenne, 51100 Reims, France
Author contributions: Memeo R and Sangiuolo F contributed to study conception and design; Piardi T contributed to acquisition of the data; Memeo R, Pessaux P and Sommacale D contributed to drafting of manuscript; Memeo R and Pessaux P contributed to critical review.
Conflict-of-interest statement: No conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Patrick Pessaux, MD, PhD, Professor, Hepato-Biliary and Pancreatic Surgical Unit, General, Digestive and Endocrine Surgery, IRCAD, IHU Mix-Surg, Institute for Minimally Invasive Image-Guided Surgery, University of Strasbourg, 1 place de l’Hopital, 67091 Strasbourg, France. patrick.pessaux@chru-strasbourg.fr
Telephone: +33-3-69550552 Fax: +33-3-69551745
Received: April 28, 2015
Peer-review started: May 5, 2015
First decision: June 25, 2015
Revised: November 9, 2015
Accepted: December 1, 2015
Article in press: December 2, 2015
Published online: December 18, 2015
Processing time: 225 Days and 21.6 Hours
Abstract

Biliary complications (BC) currently represent a major source of morbidity after liver transplantation. Although refinements in surgical technique and medical therapy have had a positive influence on the reduction of postoperative morbidity, BC affect 5% to 25% of transplanted patients. Bile leak and anastomotic strictures represent the most common complications. Nowadays, a multidisciplinary approach is required to manage such complications in order to prevent liver failure and retransplantation.

Keywords: Biliary complication; Bile leak; Anastomotic stricture; Endoscopic treatment; Liver transplantation

Core tip: Biliary complications (BC) represent the downside of liver transplantation, impacting postoperative morbidity as well as patient and graft survival. In this paper, we will analyze the most common BC, along with diagnosis, management and treatment modalities.