Miyoshi H, Mimura S, Nomura T, Tani J, Morishita A, Kobara H, Mori H, Yoneyama H, Deguchi A, Himoto T, Yamamoto N, Okano K, Suzuki Y, Masaki T. A rare case of hyaline-type Castleman disease in the liver. World J Hepatol 2013; 5(7): 404-408 [PMID: 23898375 DOI: 10.4254/wjh.v5.i7.404]
Corresponding Author of This Article
Hisaaki Miyoshi, MD, Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan. hmiyoshi@med.kagawa-u.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Hisaaki Miyoshi, Shima Mimura, Takako Nomura, Joji Tani, Asahiro Morishita, Hideki Kobara, Hirohito Mori, Hirohito Yoneyama, Akihiro Deguchi, Takashi Himoto, Tsutomu Masaki, Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan
Naoki Yamamoto, Keiichi Okano, Yasuyuki Suzuki, Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan
Author contributions: Miyoshi H and Masaki T designed the report; Miyoshi H, Mimura S, Nomura T, Tani J, Morishita A, Kobara H, Mori H, Yoneyama H, Deguchi A and Himoto T were attending doctors for the patients; Yamamoto N, Okano K and Suzuki Y performed surgical operations; Masaki T organized the report; and Miyoshi H wrote the paper.
Correspondence to: Hisaaki Miyoshi, MD, Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan. hmiyoshi@med.kagawa-u.ac.jp
Telephone: +81-87-8912156 Fax: +81-87-8912158
Received: May 5, 2013 Revised: May 27, 2013 Accepted: June 19, 2013 Published online: July 27, 2013 Processing time: 80 Days and 16 Hours
Abstract
Castleman disease often develops in the neck, mediastinum and pulmonary hilum. Its onset in the peritoneal cavity is very rare. The patient, a woman in her 70s, was referred to our department for a detailed examination of an abdominal mass. On abdominal ultrasonography, computed tomography scan, magnetic resonance imaging and positron emission tomography, a mass approximately 15 mm in diameter was noted in the hepatic S6. We attempted radical treatment and conducted a laparoscope-assisted right lobectomy. On the basis of histopathological findings, the patient was diagnosed as having hyaline type Castleman disease in the liver, a very rare condition.
Core tip: We report a very rare case of hyaline-type Castleman disease in the liver. Castleman disease can occur wherever lymphoid tissue is found, although it rarely appears in the abdominal cavity, and is especially rare in the liver. The patient was suspected of having a malignant liver tumor because of positron emission tomography findings. No findings from diagnostic imaging specific to Castleman disease are known and it is, therefore, difficult to make a predictive diagnosis.
