Case Report
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World J Hepatol. Mar 27, 2013; 5(3): 145-148
Published online Mar 27, 2013. doi: 10.4254/wjh.v5.i3.145
Liver transplantation for recurrent hepatic adenoma
Giovanni Vennarecci, Roberto Santoro, Mario Antonini, Cecilia Ceribelli, Andrea Laurenzi, Enrico Moroni, Mirco Burocchi, Pasquale Lepiane, Giuseppe Maria Ettorre
Giovanni Vennarecci, Roberto Santoro, Cecilia Ceribelli, Andrea Laurenzi, Enrico Moroni, Mirco Burocchi, Pasquale Lepiane, Giuseppe Maria Ettorre, Division of Liver Transplantation, San Camillo Hospital, 00151 Rome, Italy
Mario Antonini, Intensive Care Unit, National Institute for Infectious Disease, “Lazzaro Spallanzani”, 00151 Rome, Italy
Author contributions: Vennarecci G designed the study and wrote the paper; Santoro R analyzed the data; Antonini M and Lepiane P revised the article; Ceribelli C, Laurenzi A, Moroni E and Burocchi M collected the data; Ettorre GM designed study and final approval.
Correspondence to: Giovanni Vennarecci, MD, Division of Liver Transplantation, San Camillo Hospital, circ.ne Gianicolense 87, 00151 Rome, Italy. gvennarecci@scamilloforlanini.rm.it
Telephone: +39-338-4661336 Fax: +39-6-58704719
Received: September 7, 2012
Revised: December 7, 2012
Accepted: January 23, 2013
Published online: March 27, 2013
Abstract

Hepatic adenoma (HA) is a rare indication for liver transplantation (LTx). So far 20 cases of LTx for HA are reported in PubMed. In rare cases HA presents as multiple hepatic adenomas or recurrent adenoma after initial liver resection and in such cases LTx is the only potential cure and prevents the risk of bleeding or cancer transformation into hepatocellular carcinoma. We report the case of a 56 years old lady who underwent a left hepatectomy for giant adenoma in 2005 and resection of segment V-VI for recurrence of liver adenoma in 2007. She developed a second recurrence of HA with 3 new lesions in the right liver in 2008. The patient underwent LTx. After 3 years the patient is alive with no evidence of disease. LTx is indicated in patients with HA in which resection is not technically feasible.

Keywords: Liver transplantation, Liver adenoma, Liver resection, Recurrent disease, Immunosuppression