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©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
Acute renal failure associated with acute non-fulminant hepatitis B
Tomoya Kishi, Yuji Ikeda, Tsuyoshi Takashima, Shuichi Rikitake, Motoaki Miyazono, Toshihiko Mizuta, Kazuma Fujimoto, Department of Internal Medicine, Saga University Faculty of Medicine, Saga 849-8501, Japan
Shigehisa Aoki, Department of Pathology and Biodefense, Center for Research, Saga University Faculty of Medicine, Saga 849-8501, Japan
Takanobu Sakemi, Development in Higher Education, Saga University Faculty of Medicine, Saga 849-8501, Japan
Author contributions: All individuals who materially contributed to the information presented are listed as co-authors; all authors listed made significant contribution to the work and have reviewed and approved the manuscript.
Correspondence to: Yuji Ikeda, MD, PhD, Department of Internal Medicine, Saga University Faculty of Medicine, 5-1-1 Nabeshima, Saga 849-8501, Japan. ikedayuu@cc.saga-u.ac.jp
Telephone: +81-952-342371 Fax: +81-952-342017
Received: February 28, 2012
Revised: November 4, 2012
Accepted: November 17, 2012
Published online: February 27, 2013
Revised: November 4, 2012
Accepted: November 17, 2012
Published online: February 27, 2013
Abstract
A 38-year-old female presenting with a high fever of 39 °C developed severe liver dysfunction and acute renal failure (ARF). In tests for a hepatitis associated virus, an Immunoglobulin M-anti-hepatitis B virus core antibody was the only positive finding. Moreover, the progression of ARF coincided with the pole period of liver damage and all the other assumed causes for the ARF were unlikely. Therefore, this case was diagnosed as ARF caused by acute hepatitis B. ARF associated with non-fulminant hepatitis has been infrequently reported, usually in association with acute hepatitis A. This case is considered to be an extremely rare and interesting case.
Keywords: Acute hepatitis B; Acute renal failure; Non-fulminant hepatitis; Acute tubular necrosis; Hyperimmune response