Case Report
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World J Hepatol. Jul 27, 2010; 2(7): 289-291
Published online Jul 27, 2010. doi: 10.4254/wjh.v2.i7.289
Paraparesis caused by transarterial chemoembolization: A case report
Kashif Tufail, Victor Araya, Ashaur Azhar, David Hertzog, Kamran Khanmoradi, Jorge Ortiz
Kashif Tufail, Victor Araya, Ashaur Azhar, Department of Hepatology, Albert Einstein Medical Center, Philadelphia, PA 19141, United States
David Hertzog, Department of Radiology, Albert Einstein Medical Center, Philadelphia, PA 19141, United States
Kamran Khanmoradi, Jorge Ortiz, Department of Transplant Surgery, Albert EinsteinMedical Center, Philadelphia, PA 19141, United States
Author contributions: Tufail K, Araya V, Azhar A, Hertzog D, Khanmoradi K and Ortiz J contributed equally to this work and were responsible for formatting, editing, technical assistance, literature search and writing; Tufail K, Araya V and Ortiz JA were responsible for the concept and manuscript writing; and Hertzog D edited and formatted figures and provided valuable information regarding the TACE procedure in this patient.
Correspondence to: Kashif Tufail, MD, FACP, Department of Hepatology, Albert Einstein Medical Center, 5501 Old York Road, Klein 509, Philadelphia, PA 19141, United States. kashif_tufail@yahoo.com
Telephone: +1-215-4568242 Fax: +1-215-4568058
Received: April 23, 2010
Revised: June 29, 2010
Accepted: July 6, 2010
Published online: July 27, 2010
Abstract

Transarterial chemoembolization (TACE) is an effective modality for the treatment of Hepatocellular Carcinoma. It is used to treat small tumors and to downstage large tumors to meet liver transplant criteria. TACE can be associated with multiple side effects, including fever, right upper quadrant pain, nausea, vomiting, hepatic failure, hepatic encephalopathy, cholecystitis and pancreatitis. Neurological complications after TACE are rare, usually caused by cerebral embolism, and confirmed by means of imaging studies. Spinal cord ischemia secondary to TACE is extremely rare and can lead to significant morbidity. We report a case of paraparesis caused by TACE with normal imaging and nerve conduction studies, suggestive of localized vasculitis.

Keywords: Transarterial chemoembolization; Paraparesis; Spinal cord ischemia; Hepatocellular carcinoma