Heidecke S, Stippel DL, Hoelscher AH, Wedemeyer I, Dienes HP, Drebber U. Simultaneous occurrence of a hepatocellular carcinoma and a hepatic non-Hodgkin’s lymphoma infiltration. World J Hepatol 2010; 2(6): 246-250 [PMID: PMC2998970 DOI: 10.4254/wjh.v2.i6.246]
Corresponding Author of This Article
Sabine Heidecke, MD, Department of General-, Visceral- and Cancer Surgery, University Hospital of Cologne, Kerpener Str. 62, Cologne 50937, Germany. sabine.heidecke@uk-koeln.de
Article-Type of This Article
Case Report
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World J Hepatol. Jun 27, 2010; 2(6): 246-250 Published online Jun 27, 2010. doi: 10.4254/wjh.v2.i6.246
Simultaneous occurrence of a hepatocellular carcinoma and a hepatic non-Hodgkin’s lymphoma infiltration
Sabine Heidecke, Dirk L Stippel, Arnulf H Hoelscher, Inga Wedemeyer, Hans-Peter Dienes, Uta Drebber
Sabine Heidecke, Dirk L Stippel, Arnulf H Hoelscher, Department of General-, Visceral- and Cancer Surgery, University Hospital of Cologne, Cologne 50937, Germany
Inga Wedemeyer, Hans-Peter Dienes, Uta Drebber, Department of Pathology, University Hospital of Cologne, Cologne 50937, Germany
Author contributions: Heidecke S did the research of this project and wrote the case report; Stippel DL did the laparoscopic segmentectomy; Hoelscher AH is the head of department of surgery; and Wedemeyer I, Dienes HP and Drebber U did the pathological examinations.
Correspondence to: Sabine Heidecke, MD, Department of General-, Visceral- and Cancer Surgery, University Hospital of Cologne, Kerpener Str. 62, Cologne 50937, Germany. sabine.heidecke@uk-koeln.de
Telephone: +49-176-21906869
Received: February 8, 2010 Revised: May 17, 2010 Accepted: May 24, 2010 Published online: June 27, 2010
Abstract
To investigate the simultaneous occurrence of hepatocellular carcinoma and non-Hodgkin’s lymphoma, we report the case of a 70 year old patient with a primary diagnosis of non-Hodgkin’s lymphoma in 2002. In a routine follow up investigation of his chronic lymphocytic leukemia a newly detected mass in the Couinaud's segments 2 and 3 was found. No hepatitis C virus or hepatitis B virus infection or cirrhosis was evident. After laparoscopic segmentectomy the histological examination revealed a hepatocellular carcinoma. While the relation between liver parenchyma damages and hepatocellular carcinoma or non-Hodgkin’s lymphoma is well known, only a few publications have focused on the coexistence of hepatocellular carcinoma and non-Hodgkin’s lymphoma. With this case we demonstrate the coexistence of these diseases without having a predamaged liver parenchyma.
