Zhang YJ, Chen MS. Role of radiofrequency ablation in the treatment of small hepatocellular carcinoma. World J Hepatol 2010; 2(4): 146-150 [PMID: 21160987 DOI: 10.4254/wjh.v2.i4.146]
Corresponding Author of This Article
Min-Shan Chen, Professor, Department of Hepatobiliary Surgery, Cancer Center, Sun Yat-Sen University, 651 Dongfeng Road East, Guangzhou 510060, Guangdong Province, China. cms64@21cn.com
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Review
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World J Hepatol. Apr 27, 2010; 2(4): 146-150 Published online Apr 27, 2010. doi: 10.4254/wjh.v2.i4.146
Role of radiofrequency ablation in the treatment of small hepatocellular carcinoma
Yao-Jun Zhang, Min-Shan Chen
Yao-Jun Zhang, Min-Shan Chen, Department of Hepatobiliary Surgery, Cancer Center, Sun Yat-Sen University, 651 Dongfeng Road East, Guangzhou 510060, Guangdong Province, China
Author contributions: Both Zhang YJ and Chen MS contributed to the conception and design of this study, acquisition of data, and analysis and interpretation of data; In addition, they were both responsible for manuscript writing, including drafting the article and revising it critically for important intellectual content; Chen MS was also responsible for supportive work, including acquisition of funding, administration, technology and materials support and supervision.
Correspondence to: Min-Shan Chen, Professor, Department of Hepatobiliary Surgery, Cancer Center, Sun Yat-Sen University, 651 Dongfeng Road East, Guangzhou 510060, Guangdong Province, China. cms64@21cn.com
Telephone: +86-20-87343117 Fax: +86-20-87343117
Received: June 23, 2009 Revised: March 19, 2010 Accepted: March 26, 2010 Published online: April 27, 2010
Abstract
Radiofrequency ablation (RFA), one of the most advanced loco-regional ablative therapeutic methods, is widely utilized in the treatment of hepatocellular carcinoma (HCC). Because of its minimal invasiveness and high efficacy, RFA has been regarded as a curative therapy as alternative to surgical resection and liver transplantation. It brings new hope and a new treatment pattern for small HCC. In this article, we summarize the important role of RFA in the treatment of small HCC according to our clinical experience over six years. The prognosis of small HCC after RFA is comparable to that of surgical resection but with higher safety, less complications, wider applicability, and good long-term survival. RFA will play a more and more important role in the clinical treatment of small HCC.
