Tulading A, Wu J, Zhang YF, Mamuti A, Azhati Y, Lv CH, Tuersunmaimaiti A, Tuxun T. Immunological landscape of hepatic alveolar echinococcosis: A bibliometric analysis. World J Hepatol 2025; 17(2): 102001 [DOI: 10.4254/wjh.v17.i2.102001]
Corresponding Author of This Article
Tuerhongjiang Tuxun, PhD, Professor, Department of Liver & Laparoscopic Surgery, Center of Digestive and Vascular Surgery, First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan Road, Urumqi 830054, Xinjiang Uygur Autonomous Region, China. turgunbay@163.com
Research Domain of This Article
Parasitology
Article-Type of This Article
Scientometrics
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Aliya Tulading, Jing Wu, Yun-Fei Zhang, Alimujiang Mamuti, Yilizhati Azhati, Chun-Hui Lv, Abudusalamu Tuersunmaimaiti, Tuerhongjiang Tuxun, Department of Liver & Laparoscopic Surgery, Center of Digestive and Vascular Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
Co-first authors: Aliya Tulading and Jing Wu.
Author contributions: Tulading A contributed to conceptualization and wrote the manuscript; Jing W analyzed data and contributed to software and visualization; Tulading A and Jing W contributed equally as co-first authors; Tulading A, Zhang YF, Mamuti A, Azhati Y, Lv CH, and Tuersunmaimaiti A collected and analyzed data; Tuxun T contributed to financial support, administration, and final approval of the manuscript; and all authors contributed to the writing and have read and approved the final content of this manuscript.
Supported by National Natural Science Foundation of China, No. 82270632 and No. 82260411.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tuerhongjiang Tuxun, PhD, Professor, Department of Liver & Laparoscopic Surgery, Center of Digestive and Vascular Surgery, First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan Road, Urumqi 830054, Xinjiang Uygur Autonomous Region, China. turgunbay@163.com
Received: October 8, 2024 Revised: December 11, 2024 Accepted: January 23, 2025 Published online: February 27, 2025 Processing time: 138 Days and 9.5 Hours
Abstract
BACKGROUND
Hepatic alveolar echinococcosis (HAE) is a chronic parasitic disease caused by the larval stage of Echinococcus multilocularis. Although significant research has been conducted on the pathogenesis and immunological aspects of HAE, comprehensive bibliometric analyses in this area are still lacking. This study sought to fill this gap by systematically analyzing the immunological literature on HAE using bibliometric methods.
AIM
To identify research trends, key contributors, and emerging developments and offer insights to guide future research in this field.
METHODS
Research articles on HAE published between 1983 and 2023 were retrieved from the Web of Science Core Collection database. A total of 319 articles were selected for bibliometric analysis, which was conducted using the CiteSpace and VOSviewer software. The analysis focused on key variables such as publication volume, authors, journals, countries, references, and keywords.
RESULTS
The analysis revealed a significant increase in research on HAE over the past four decades, particularly after 1995. China and Switzerland emerged as the leading countries in terms of publication volume, with Bruno Gottstein and Vuitton DA identified as the most influential authors in this field. Key research areas include the interaction between the pathogen and the host immune system, as well as advances in disease diagnosis and treatment strategies. The keyword co-occurrence analysis highlighted the primary themes and identified emerging trends within the research landscape.
CONCLUSION
This study provides a comprehensive framework for understanding HAE immunology and highlights research hotspots, future directions, key contributors, and the importance of international cooperation.
Core Tip: This study conducted a unique, comprehensive bibliometric analysis of immunological research on hepatic alveolar echinococcosis, highlighting the significant growth in publications since 1995. It identifies key contributors, including top authors and countries, and emphasizes emerging research areas, such as pathogen-host interactions and diagnostic advancements. These findings offer valuable insights for guiding future research on hepatic alveolar echinococcosis and for promoting international collaboration.
