Jin LY, Wang K, Xu BT. High metabolic dysfunction-associated steatotic liver disease prevalence in type 2 diabetes: Urgent need for integrated screening and lifestyle intervention. World J Hepatol 2025; 17(1): 103409 [DOI: 10.4254/wjh.v17.i1.103409]
Corresponding Author of This Article
Lei-Yang Jin, MD, Assistant Professor, Department of Hepatobiliary Surgery, Zhuji People’s Hospital, No. 9 Jianmin Road, Taozhu Street, Zhuji 311800, Zhejiang Province, China. 15968561792@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Jan 27, 2025; 17(1): 103409 Published online Jan 27, 2025. doi: 10.4254/wjh.v17.i1.103409
High metabolic dysfunction-associated steatotic liver disease prevalence in type 2 diabetes: Urgent need for integrated screening and lifestyle intervention
Lei-Yang Jin, Kai Wang, Bo-Tao Xu
Lei-Yang Jin, Kai Wang, Department of Hepatobiliary Surgery, Zhuji People’s Hospital, Zhuji 311800, Zhejiang Province, China
Bo-Tao Xu, Department of Cardiothoracic Surgery, Zhuji People’s Hospital, Zhuji 311800, Zhejiang Province, China
Author contributions: Jin LY contributed to conceptualized, designed the study and created the artwork; Wang K contributed to data curation and formal Analysis; Xu BT conducted the literature review, performed the data analysis and interpretation, and reviewed and edited the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lei-Yang Jin, MD, Assistant Professor, Department of Hepatobiliary Surgery, Zhuji People’s Hospital, No. 9 Jianmin Road, Taozhu Street, Zhuji 311800, Zhejiang Province, China. 15968561792@163.com
Received: November 18, 2024 Revised: December 15, 2024 Accepted: December 18, 2024 Published online: January 27, 2025 Processing time: 49 Days and 2.3 Hours
Abstract
This letter discusses the recent study by Mukherjee et al, which identifies a significant prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) among newly diagnosed type 2 diabetes mellitus (T2DM) patients in Bihar, India, and underscores the pressing need for integrated MASLD management within T2DM care. With 72.3% of the study cohort affected by MASLD, implementing routine liver function tests and ultrasound screenings is recommended as a standard practice in diabetes care, especially in regions with high prevalence rates. The study also advocates for dietary and lifestyle modifications, particularly the reduction of saturated fats, to slow MASLD progression. Patient education on monitoring body mass index and waist circumference, coupled with the integration of these metrics into digital health records, could enhance patient involvement and support proactive health management. Moreover, the letter emphasizes the advantages of developing a region-specific MASLD risk model that incorporates local dietary patterns and socioeconomic factors. Continued research into genetic and environmental determinants of MASLD remains essential for advancing our understanding of its etiology and informing targeted public health strategies.
Core Tip: The high prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in newly diagnosed type 2 diabetes mellitus patients emphasizes the importance of regular liver health assessments in diabetes care. Screening should include liver function tests and ultrasound imaging for early detection. Dietary changes, such as reducing saturated fat, along with lifestyle interventions, can improve liver health. Educating patients on monitoring body mass index and waist circumference promotes proactive health management. A region-specific MASLD risk model could enhance screening accuracy, while further research into genetic and environmental factors may reveal the disease’s mechanisms and guide prevention strategies.
