Gialanella JP, Steidl T, Korpela K, Grandhi MS, Langan RC, Alexander HR, Hudacko RM, Ecker BL. Hepatic pseudotumor associated with Strongyloides infection: A case report. World J Hepatol 2023; 15(12): 1338-1343 [PMID: 38223414 DOI: 10.4254/wjh.v15.i12.1338]
Corresponding Author of This Article
Brett L Ecker, MD, Assistant Professor, Surgical Oncologist, Department of Surgical Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany St, New Brunswick, NJ 08901, United States. brett.ecker@rutgers.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Dec 27, 2023; 15(12): 1338-1343 Published online Dec 27, 2023. doi: 10.4254/wjh.v15.i12.1338
Hepatic pseudotumor associated with Strongyloides infection: A case report
Jessica P Gialanella, Tyler Steidl, Kokkola Korpela, Miral S Grandhi, Russell C Langan, H Richard Alexander, Rachel M Hudacko, Brett L Ecker
Jessica P Gialanella, Miral S Grandhi, Russell C Langan, H Richard Alexander, Brett L Ecker, Department of Surgical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, United States
Tyler Steidl, Rutgers New Jersey Medical School, Newark, NJ 07103, United States
Kokkola Korpela, Department of Infectious Disease, Cooperman Barnabas Medical Center, Livingston, NJ 07039, United States
Rachel M Hudacko, Department of Pathology and Labratory Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, United States
Author contributions: Grandhi MS, Alexander HR, and Ecker BL contributed to the conceptualization and supervision of the research; Gialanella JP, Alexander RH, Korpela K, and Ecker BL contributed to data collection and data analysis; Gialanella JP and Ecker BL contributed to the manuscript writing; All authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE checklist (2016) and the manuscript was prepared and revised according to this checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Brett L Ecker, MD, Assistant Professor, Surgical Oncologist, Department of Surgical Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany St, New Brunswick, NJ 08901, United States. brett.ecker@rutgers.edu
Received: September 13, 2023 Peer-review started: September 13, 2023 First decision: October 16, 2023 Revised: October 21, 2023 Accepted: November 29, 2023 Article in press: November 29, 2023 Published online: December 27, 2023 Processing time: 102 Days and 15.4 Hours
Abstract
BACKGROUND
Strongyloides sterocoralis is a parasitic infection caused by a roundworm that is transmitted through soil contaminated with larvae. It can infrequently cause hepatic abscesses in immunocompromised patients and is rarely reported to form hepatic lesions in immunocompetent hosts.
CASE SUMMARY
We present a case study of a 45-year-old female who presented with right upper quadrant abdominal pain and constitutional symptoms for several weeks. Cross-sectional imaging identified several malignant-appearing liver masses. Further investigation, including serological testing and histopathologic examination, revealed the presence of serum Strongyloides antibodies and hepatic granulomas with extensive necrosis. Following treatment with ivermectin for 2 wk, there was complete resolution of the liver lesions and associated symptoms.
CONCLUSION
This case highlights the importance of considering parasitic infections, such as Strongyloides, in the differential diagnosis of hepatic masses. Early recognition and appropriate treatment can lead to a favorable outcome and prevent unnecessary invasive procedures. Increased awareness among clinicians is crucial to ensure the timely diagnosis and management of such cases.
Core Tip: Hepatic pseudotumor is a clinical entity that can mimic malignant tumors of the liver. We report a rare case of hepatic pseudotumor caused by Strongyloides sterocoralis. Combined with a review of cases indexed in PubMed, we summarize the infectious causes of hepatic pseudotumor. Recognition of hepatic mass-forming parasitic infections may expedite prompt medical management.
