Fung BM, Abadir AP, Eskandari A, Levy MJ, Tabibian JH. Endoscopic ultrasound in chronic liver disease. World J Hepatol 2020; 12(6): 262-276 [PMID: 32742569 DOI: 10.4254/wjh.v12.i6.262]
Corresponding Author of This Article
James H Tabibian, MD, PhD, FACP, Associate Professor, Director of Endoscopy, Department of Medicine, Olive View-UCLA Medical Center, 14445 Olive View Dr., 2B-182, Sylmar, CA 91342, United States. jtabibian@dhs.lacounty.gov
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Jun 27, 2020; 12(6): 262-276 Published online Jun 27, 2020. doi: 10.4254/wjh.v12.i6.262
Endoscopic ultrasound in chronic liver disease
Brian M Fung, Alexander P Abadir, Armen Eskandari, Michael J Levy, James H Tabibian
Brian M Fung, Department of Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
Alexander P Abadir, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868, United States
Armen Eskandari, Division of Gastroenterology and Hepatology, University of California Davis Medical Center, Sacramento, CA 95817, United States
Michael J Levy, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States
James H Tabibian, Division of Gastroenterology, Department of Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
Author contributions: Fung BM and Eskandari A reviewed the literature for relevant original studies and other content and drafted the manuscript; Abadir AP and Levy MJ reviewed the manuscript and provided figures; Tabibian JH provided supervision; all authors provided critical input and approved of the manuscript.
Conflict-of-interest statement: The authors have no financial disclosures or conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: James H Tabibian, MD, PhD, FACP, Associate Professor, Director of Endoscopy, Department of Medicine, Olive View-UCLA Medical Center, 14445 Olive View Dr., 2B-182, Sylmar, CA 91342, United States. jtabibian@dhs.lacounty.gov
Received: February 29, 2020 Peer-review started: February 29, 2020 First decision: April 7, 2020 Revised: May 9, 2020 Accepted: May 28, 2020 Article in press: May 28, 2020 Published online: June 27, 2020 Processing time: 119 Days and 23.9 Hours
Abstract
Endoscopic ultrasound (EUS) is a minimally invasive diagnostic and therapeutic modality with a number of established as well as evolving uses in patients with chronic liver disease. Compared to other diagnostic tools such as cross-sectional imaging or conventional endoscopy, EUS has been shown to increase diagnostic sensitivity and therapeutic success for many clinical scenarios and applications with a low rate of adverse events. In this review, we discuss and focus on the current and growing role of EUS in the evaluation and/or treatment of hepatobiliary masses, hepatic parenchymal disease, portal hypertension, esophageal and other varices, and indeterminate biliary strictures.
Core tip: Endoscopic ultrasound (EUS) is a minimally invasive diagnostic and therapeutic modality with numerous existing and emerging applications in patients with chronic liver disease. In this review, we discuss the role of EUS in the evaluation of hepatobiliary masses, hepatic parenchymal disease, portal hypertension, and indeterminate biliary strictures. We also review how EUS can serve as an ancillary tool to conventional endoscopic and other therapies, including the use of EUS for the treatment of variceal bleeding.
