Shah AR, Al-Hanayneh M, Chowdhry M, Bilal M, Singh S. Endoscopic ultrasound guided liver biopsy for parenchymal liver disease. World J Hepatol 2019; 11(4): 335-343 [PMID: 31114638 DOI: 10.4254/wjh.v11.i4.335]
Corresponding Author of This Article
Shailendra Singh, MD, Doctor, Division of Gastroenterology, Department of Internal Medicine, West Virginia University, 3110 MacCorkle Ave SE, Charleston, WV 25304, United States. shail121@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Aun Raza Shah, Department of Internal Medicine, MetroHealth Medical Center, Cleveland, OH 44109, United States
Muhannad Al-Hanayneh, Mohammad Bilal, Division of Gastroenterology and Hepatology, the University of Texas Medical Branch, Galveston, TX 77555, United States
Monica Chowdhry, Shailendra Singh, Division of Gastroenterology, Department of Internal Medicine, West Virginia University, Charleston, WV 25304, United States
Author contributions: Bilal M and Singh S designed the outline for the manuscript; Shah AR, Al-Hanayneh M, Chowdhry M and Bilal M wrote critical portions of the initial manuscript; Bilal M and Singh S provided expert opinion, and edited the final version of the manuscript.
Conflict-of-interest statement: The authors report no conflict of interest and have no financial disclosures with respect to this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shailendra Singh, MD, Doctor, Division of Gastroenterology, Department of Internal Medicine, West Virginia University, 3110 MacCorkle Ave SE, Charleston, WV 25304, United States. shail121@gmail.com
Telephone: +1-412-2775244 Fax: +1-409-7723394
Received: December 28, 2018 Peer-review started: December 29, 2018 First decision: March 5, 2019 Revised: March 24, 2019 Accepted: April 8, 2019 Article in press: April 8, 2019 Published online: April 27, 2019 Processing time: 119 Days and 22.4 Hours
Abstract
Liver biopsy plays an essential role in the diagnosis, evaluation and management of a vast proportion of liver diseases. Conventionally, percutaneous and trans-jugular approaches have been used to obtain liver biopsies. Endoscopic ultrasound guided liver biopsy (EUS-LB) has emerged as a safe and effective alternate in the past two decades. EUS-LB carries a role in evaluation of both benign and malignant diseases of the liver. It can offer higher resolution imaging of the liver and can detect smaller lesions than computed tomography scan of the abdomen or ultrasound scans with the option for doppler assistance to reduce complications. Current evidence demonstrates the superiority of EUS-LB for a targeted approach of focal lesion and there is also evidence of less sampling variability in heterogeneous parenchymal pathologies. These advantages combined with an improved safety profile had led to the rapid progress in the development of new techniques, equipment and procedures for EUS-LB. We provide a comprehensive review of EUS-LB for parenchymal liver disease.
Core tip: In this review, we provide a comprehensive discussion on the role of Endoscopic ultrasound guided liver biopsy (EUS-LB) in parenchymal liver disease. This article summarized the technical aspects of EUS-LB; as well as debated its advantages and disadvantages. We also highlight new advancements and recently reported research experiences.
