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For: Hayes JD, Dinkova-Kostova AT, Tew KD. Oxidative Stress in Cancer. Cancer Cell 2020;38:167-197. [PMID: 32649885 PMCID: PMC7439808 DOI: 10.1016/j.ccell.2020.06.001] [Citation(s) in RCA: 1480] [Impact Index Per Article: 296.0] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/15/2019] [Revised: 04/29/2020] [Accepted: 05/29/2020] [Indexed: 12/13/2022]
Number Cited by Other Article(s)
1
Zhu X, Xiong C, Zhou H, Wang J, Wu Y. Single-atom nanozymes for enhanced electrochemical biosensing: A review. Talanta 2025;294:128179. [PMID: 40286743 DOI: 10.1016/j.talanta.2025.128179] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/24/2025] [Revised: 03/30/2025] [Accepted: 04/17/2025] [Indexed: 04/29/2025]
2
Zhou QM, Lu YF, Yang XY, Zhang JG, Wang YN, Luo WP, Mao J, Hou J, Wu F, Wang WL, Tang GP, Bai HZ, Yu RS. Redox-driven hybrid nanoenzyme dynamically activating ferroptosis and disulfidptosis for hepatocellular carcinoma theranostics. J Colloid Interface Sci 2025;693:137611. [PMID: 40253866 DOI: 10.1016/j.jcis.2025.137611] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/26/2025] [Revised: 04/14/2025] [Accepted: 04/15/2025] [Indexed: 04/22/2025]
3
Shen T, Wang Y, Cheng L, Bode AM, Gao Y, Zhang S, Chen X, Luo X. Oxidative complexity: The role of ROS in the tumor environment and therapeutic implications. Bioorg Med Chem 2025;127:118241. [PMID: 40383035 DOI: 10.1016/j.bmc.2025.118241] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/27/2025] [Revised: 05/01/2025] [Accepted: 05/12/2025] [Indexed: 05/20/2025]
4
Shao Z, Zeng J, Dong J, Ji F, Li H, Yang R, Chen W, Li W, Wang S. An integrated non-alkaline derivatization strategy using 2,2'-dithiodipyridine and HPLC for simultaneous analysis of total and low-molecular-weight free thiols in human serum. Anal Chim Acta 2025;1358:344078. [PMID: 40374240 DOI: 10.1016/j.aca.2025.344078] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/09/2024] [Revised: 04/02/2025] [Accepted: 04/14/2025] [Indexed: 05/17/2025]
5
Hu M, Wang F, Zhu Y, Yao Y, Pei H, Liu Z, Zhang P. NADK tetramer defective mutants affect lung cancer response to chemotherapy via controlling NADK activity. Genes Dis 2025;12:101510. [PMID: 40330153 PMCID: PMC12052686 DOI: 10.1016/j.gendis.2024.101510] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/28/2024] [Revised: 10/25/2024] [Accepted: 12/18/2024] [Indexed: 05/08/2025]  Open
6
Huang Z, Li A, Huang R, Shi M, Yang R, Wang W, Huang Z, Liu Y, Wu J. Effect of xylitol on low‑density lipoprotein‑stimulated oxidative stress in THP‑1 cells. Mol Med Rep 2025;32:190. [PMID: 40341459 PMCID: PMC12076051 DOI: 10.3892/mmr.2025.13555] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/17/2024] [Accepted: 04/03/2025] [Indexed: 05/10/2025]  Open
7
Hellmann ZJ, Rehman S, Brown LM, Vasquez JC, Solomon DG, Christison-Lagay ER. Relationship Between Total Parenteral Nutrition, Ventilation, and Hepatoblastoma: A Study of 258,929 Neonatal Intensive Care Unit Admissions. Pediatr Blood Cancer 2025;72:e31741. [PMID: 40275525 DOI: 10.1002/pbc.31741] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/23/2024] [Revised: 03/09/2025] [Accepted: 04/09/2025] [Indexed: 04/26/2025]
8
MacMillan AC, Karki B, Yang J, Gertz KR, Zumwalde S, Patel JG, Czyzyk-Krzeska MF, Meller J, Cunningham JT. PRPS activity tunes redox homeostasis in Myc-driven lymphoma. Redox Biol 2025;84:103649. [PMID: 40446642 PMCID: PMC12166406 DOI: 10.1016/j.redox.2025.103649] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/27/2025] [Accepted: 04/21/2025] [Indexed: 06/18/2025]  Open
9
Lu L, Tao R. Prognostic implications of glucose metabolism pathways in colon adenocarcinoma: a comprehensive outlook on the molecular landscape and immunotherapy. Biochem Biophys Res Commun 2025;768:151961. [PMID: 40345006 DOI: 10.1016/j.bbrc.2025.151961] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/12/2025] [Revised: 03/30/2025] [Accepted: 05/05/2025] [Indexed: 05/11/2025]
10
Duan D, Yang X, Guo X, Li M, Jin X, Wang L, Xiao J, Wang X, Song P. Interaction of glaucocalyxin a with glutathione and thioredoxin reductase for triple-negative breast cancer treatment. Bioorg Chem 2025;161:108572. [PMID: 40359839 DOI: 10.1016/j.bioorg.2025.108572] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/05/2025] [Revised: 05/06/2025] [Accepted: 05/07/2025] [Indexed: 05/15/2025]
11
Mao Y, Liu X, Chu X, Chen F, Shi R, Liu Z, Wu Y, Liu Y, Bu W. Nanomedicine-Driven Modulation of Reductive Stress for Cancer Therapy. ADVANCED SCIENCE (WEINHEIM, BADEN-WURTTEMBERG, GERMANY) 2025:e01968. [PMID: 40569215 DOI: 10.1002/advs.202501968] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 01/31/2025] [Revised: 05/26/2025] [Indexed: 06/28/2025]
12
Kim SB, Lee JS, Jung CH, Cho EH, Seo HS, Lee GE, Kim HY, Lee SJ, Lee MJ, Oh HJY, Heo AJ, Han DH, Kwon YT, Ji CH. The Arg/N-degron pathway mediates the secretion of apoptotic exosomes under oxidative stress in cancer cell. iScience 2025;28:112637. [PMID: 40520087 PMCID: PMC12167491 DOI: 10.1016/j.isci.2025.112637] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/21/2024] [Revised: 07/08/2024] [Accepted: 05/07/2025] [Indexed: 06/18/2025]  Open
13
Hu J, Yuan Z, Shu Y, Ren J, Yang J, Tang L, Wei X, Liu Y, Jin F, Xiao Q, Chen X, Wu N, Zhao W, Li Z, Zhang L. NRF2 maintains redox balance via ME1 and NRF2 inhibitor synergizes with venetoclax in NPM1-mutated acute myeloid leukemia. Cancer Metab 2025;13:32. [PMID: 40533864 PMCID: PMC12177962 DOI: 10.1186/s40170-025-00401-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/29/2025] [Accepted: 06/12/2025] [Indexed: 06/22/2025]  Open
14
Syahputra RA, Ahmed A, Asriadi, Barus AGB, Putri SK, Tan MW, Chandra QM, Brathennovic, Angiosaki Y, Lu FC, Clister D, Prananda AT, Halim P, Ribeiro RIMDA, Nurkolis F, Dalimunthe A. Ergothioneine as a Functional Nutraceutical: Mechanisms, Bioavailability, and Therapeutic Implications. J Nutr Biochem 2025:110006. [PMID: 40541582 DOI: 10.1016/j.jnutbio.2025.110006] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/21/2025] [Revised: 06/06/2025] [Accepted: 06/13/2025] [Indexed: 06/22/2025]
15
Yang X, Yu L, Shao M, Yang H, Qi K, He G, Wang L, Kong D, Gu J, Xu X, Wang L. N6-methyladenosine-modified GPX2 impacts cancer cell stemness and TKI resistance through regulating of redox metabolism. Cell Death Dis 2025;16:458. [PMID: 40533443 PMCID: PMC12177039 DOI: 10.1038/s41419-025-07764-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/17/2024] [Revised: 05/13/2025] [Accepted: 06/03/2025] [Indexed: 06/22/2025]
16
Alonso-García S, Sánchez-Uceta P, Moreno-SanJuan S, Casado J, Puentes-Pardo JD, Khaldy H, Lopez-Pérez D, Zurita-Saavedra MS, González-Puga C, Carazo A, León J. Regulation of Stemness by NR1D2 in Colorectal Cancer. Biomedicines 2025;13:1500. [PMID: 40564218 DOI: 10.3390/biomedicines13061500] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/06/2025] [Revised: 06/08/2025] [Accepted: 06/13/2025] [Indexed: 06/28/2025]  Open
17
Gao L, Liao H, Chen Y, Ye C, Huang L, Xu M, Du J, Zhang J, Huang D, Cai S, Dong H. Airway microbiota associated D-phenylalanine promotes non-small cell lung cancer metastasis through epithelial mesenchymal transition. J Transl Med 2025;23:673. [PMID: 40528221 DOI: 10.1186/s12967-025-06701-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/25/2025] [Accepted: 06/01/2025] [Indexed: 06/20/2025]  Open
18
Xia F, Sha Y, Jin Y, Yang J, Chen C, Gong B, Liu Y, Zhao Q. Autophagy inhibition amplifies anti-tumor immunity effect of dinutuximab beta on neuroblastoma via the VEGFR/AKT/mTOR and ROS/NF-κB pathways. Int Immunopharmacol 2025;158:114862. [PMID: 40378433 DOI: 10.1016/j.intimp.2025.114862] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/24/2024] [Revised: 05/08/2025] [Accepted: 05/09/2025] [Indexed: 05/18/2025]
19
Ma J, Qiu J, Wang S. Tumor Microenvironment-responsive Nanocatalyst for Targeted Chemodynamic Cancer Therapy. Adv Healthc Mater 2025:e2501746. [PMID: 40525679 DOI: 10.1002/adhm.202501746] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/04/2025] [Revised: 05/26/2025] [Indexed: 06/19/2025]
20
Znaidi R, Massiani-Beaudoin O, Mailly P, Monnet H, Bonnifet T, Joshi RL, Fuchs J. Nuclear translocation of the LINE-1 encoded ORF1 protein alters nuclear envelope integrity in human neurons. Brain Res 2025;1857:149579. [PMID: 40157412 DOI: 10.1016/j.brainres.2025.149579] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/06/2025] [Accepted: 03/17/2025] [Indexed: 04/01/2025]
21
Wang M, Xiao Y, Miao J, Zhang X, Liu M, Zhu L, Liu H, Shen X, Wang J, Xie B, Wang D. Oxidative Stress and Inflammation: Drivers of Tumorigenesis and Therapeutic Opportunities. Antioxidants (Basel) 2025;14:735. [PMID: 40563367 DOI: 10.3390/antiox14060735] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/07/2025] [Revised: 06/08/2025] [Accepted: 06/12/2025] [Indexed: 06/28/2025]  Open
22
Alves R, Ventura F, Jorge J, Marques G, Coucelo M, Diamond J, Oliveiros B, Pereira A, Freitas-Tavares P, Almeida AM, Gonçalves AC, Sarmento-Ribeiro AB. Genetic Variants in Oxidative Stress-Related Genes and Their Impact on Prognosis and Treatment Response in Chronic Myeloid Leukemia Patients. Int J Mol Sci 2025;26:5682. [PMID: 40565143 DOI: 10.3390/ijms26125682] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/15/2025] [Revised: 05/18/2025] [Accepted: 06/11/2025] [Indexed: 06/28/2025]  Open
23
Geaneotes PJ, Floreancig PE. Strategy-Level Prodrug Synthesis. Chemistry 2025;31:e202501115. [PMID: 40317559 PMCID: PMC12160975 DOI: 10.1002/chem.202501115] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/19/2025] [Revised: 04/30/2025] [Accepted: 05/02/2025] [Indexed: 05/07/2025]
24
Chen C, Carrillo ND, Chen M, Wen T, Awasthi P, Anderson RA, Cryns VL. Regulation of NRF2 by Stably associated Phosphoinositides and Small Heat Shock Proteins in Response to Stress. J Biol Chem 2025:110367. [PMID: 40516875 DOI: 10.1016/j.jbc.2025.110367] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/24/2025] [Revised: 06/02/2025] [Accepted: 06/09/2025] [Indexed: 06/16/2025]  Open
25
Deng Q, Hua A, Zhao Q, Zhang Z, Yang T, Wang Q, Yang X, Li Z. Modulating tumor acidity with hydroxyethyl starch-based nanoparticles by targeting CA9 to eliminate cancer stem cells and overcome immunosuppression. Biomaterials 2025;324:123501. [PMID: 40527086 DOI: 10.1016/j.biomaterials.2025.123501] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/16/2025] [Revised: 05/27/2025] [Accepted: 06/12/2025] [Indexed: 06/19/2025]
26
Rapozzi V, Comuzzi C, Di Giorgio E, Xodo LE. KRAS and NRF2 drive metabolic reprogramming in pancreatic cancer cells: the influence of oxidative and nitrosatice stress. Front Cell Dev Biol 2025;13:1547582. [PMID: 40567499 PMCID: PMC12187747 DOI: 10.3389/fcell.2025.1547582] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/18/2024] [Accepted: 05/26/2025] [Indexed: 06/28/2025]  Open
27
Huang Q, Jing Y, Xiong L, Li L, Feng J, Cheng J. The interplay between driver mutation and oxidative stress in colorectal cancer: from pathogenesis to therapeutics. J Transl Med 2025;23:635. [PMID: 40490762 DOI: 10.1186/s12967-025-06640-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/25/2025] [Accepted: 05/23/2025] [Indexed: 06/11/2025]  Open
28
Tamir TY, Chaudhary S, Li AX, Trojan SE, Flower CT, Vo P, Cui Y, Davis JC, Mukkamala R, Venditti FN, Hillis AL, Toker A, Vander Heiden MG, Spinelli JB, Kennedy NJ, Davis RJ, White FM. Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity. Mol Cell 2025;85:2211-2229.e8. [PMID: 40441152 PMCID: PMC12147527 DOI: 10.1016/j.molcel.2025.05.007] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/26/2024] [Revised: 02/24/2025] [Accepted: 05/05/2025] [Indexed: 06/11/2025]
29
Xu Q, Liu P, Nie Q, Chu Y, Yao X, Fang J, Zhang J. Structural simplification of quaternary benzophenanthridine alkaloids generating a candidate for the treatment of non-small cell lung cancer. Eur J Med Chem 2025;290:117551. [PMID: 40147342 DOI: 10.1016/j.ejmech.2025.117551] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/15/2025] [Revised: 03/20/2025] [Accepted: 03/21/2025] [Indexed: 03/29/2025]
30
Kafeel S, Palmiero G, Salzillo A, Ragone A, Naviglio S, Sapio L. Unravelling the Adiponectin Hallmark and Exploring the Therapeutic Potential of Its Receptor Agonists in Cancer Metabolic Reprogramming. Biomolecules 2025;15:820. [PMID: 40563460 DOI: 10.3390/biom15060820] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/30/2025] [Revised: 05/29/2025] [Accepted: 06/01/2025] [Indexed: 06/28/2025]  Open
31
Sun Y, He J, Chen W, Wang Y, Wang K, Zhou M, Zheng Y. Inhalable DNase I@Au hybrid nanoparticles for radiation sensitization and metastasis inhibition by elimination of neutrophil extracellular traps. Biomaterials 2025;317:123095. [PMID: 39813970 DOI: 10.1016/j.biomaterials.2025.123095] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/18/2024] [Revised: 01/03/2025] [Accepted: 01/07/2025] [Indexed: 01/18/2025]
32
Zhao C, Wang H, Xu C, Fang F, Gao L, Zhai N, Zhong Y, Wang X. The critical role of the Hippo signaling pathway in renal fibrosis. Cell Signal 2025;130:111661. [PMID: 39988289 DOI: 10.1016/j.cellsig.2025.111661] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2024] [Revised: 02/12/2025] [Accepted: 02/14/2025] [Indexed: 02/25/2025]
33
Wu M, Sheng J, Xie Q, Qi Y, Zhao Y, Zhang S. Recent advances in stimuli-responsive hyaluronic acid-based nanodelivery systems for cancer treatment: A review. Int J Biol Macromol 2025;316:144357. [PMID: 40403810 DOI: 10.1016/j.ijbiomac.2025.144357] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/05/2025] [Revised: 05/09/2025] [Accepted: 05/16/2025] [Indexed: 05/24/2025]
34
Zhang X, Nguyen MH. Metabolic dysfunction-associated steatotic liver disease: A sexually dimorphic disease and breast and gynecological cancer. Metabolism 2025;167:156190. [PMID: 40081614 DOI: 10.1016/j.metabol.2025.156190] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/02/2025] [Revised: 02/26/2025] [Accepted: 03/09/2025] [Indexed: 03/16/2025]
35
Wang K, Baird L, Yamamoto M. The clinical-grade CBP/ p300 inhibitor CCS1477 represses the global NRF2-dependent cytoprotective transcription program and re-sensitizes cancer cells to chemotherapeutic drugs. Free Radic Biol Med 2025;233:102-117. [PMID: 40127850 DOI: 10.1016/j.freeradbiomed.2025.03.034] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/12/2025] [Revised: 03/14/2025] [Accepted: 03/22/2025] [Indexed: 03/26/2025]
36
Wan J, Shi JH, Shi M, Huang H, Zhang Z, Li W, Guo C, Bao R, Yu X, Han Q, Du X, Li S, Ye Y, Cui X, Li X, Li JH, Zou Q. Lactate dehydrogenase B facilitates disulfidptosis and exhaustion of tumour-infiltrating CD8+ T cells. Nat Cell Biol 2025;27:972-982. [PMID: 40461882 DOI: 10.1038/s41556-025-01673-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/14/2024] [Accepted: 04/16/2025] [Indexed: 06/19/2025]
37
Yang W, Zhu Z, Zhou C, Chen J, Ou J, Tong H, Iyaswamy A, Chen P, Wei X, Yang C, Xiao W, Wang J, Zhang W. The rheumatoid arthritis drug Auranofin targets peroxiredoxin 1 and peroxiredoxin 2 to trigger ROS-endoplasmic reticulum stress axis-mediated cell death and cytoprotective autophagy. Free Radic Biol Med 2025;233:1-12. [PMID: 40089079 DOI: 10.1016/j.freeradbiomed.2025.03.016] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/14/2025] [Revised: 02/26/2025] [Accepted: 03/12/2025] [Indexed: 03/17/2025]
38
Xu L, Lei Z, Wang Q, Jiang Q, Xing B, Li X, Guo X, Wang Z, Li S, Huang Y, Lei T. Androgen Receptor Mediates Dopamine Agonist Resistance by Regulating Intracellular Reactive Oxygen Species in Prolactin-Secreting Pituitary Adenoma. Antioxid Redox Signal 2025;42:954-972. [PMID: 39360800 DOI: 10.1089/ars.2024.0611] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/07/2024]
39
Ngo HV, Nguyen HD, Lee BJ. Triple synergistic cancer targeting strategies utilizing redox-sensitive fattigated hyaluronic acid nanoparticles encapsulating doxorubicin. Int J Biol Macromol 2025;313:144168. [PMID: 40379189 DOI: 10.1016/j.ijbiomac.2025.144168] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/14/2025] [Revised: 03/30/2025] [Accepted: 05/11/2025] [Indexed: 05/19/2025]
40
Liu Y, Wu G, Feng L, Li J, Xia Y, Guo W, Zhao K. Harnessing Antioxidants in Cancer Therapy: Opportunities, Challenges, and Future Directions. Antioxidants (Basel) 2025;14:674. [PMID: 40563308 DOI: 10.3390/antiox14060674] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/06/2025] [Revised: 05/27/2025] [Accepted: 05/29/2025] [Indexed: 06/28/2025]  Open
41
Li Z, Lu Y, Wang L, Shi L, Wang T. Reactive oxygen species-dependent nanomedicine therapeutic modalities for gastric cancer. NANOSCALE ADVANCES 2025;7:3210-3227. [PMID: 40308560 PMCID: PMC12038724 DOI: 10.1039/d5na00321k] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 04/06/2025] [Accepted: 04/15/2025] [Indexed: 05/02/2025]
42
Niu Y, Zhao T, Wang X, Sun Y, Zhang Y. Molecular Dynamics Simulations of Plasma-Antifolate Drug Synergy in Cancer Therapy. Biomolecules 2025;15:773. [PMID: 40563414 DOI: 10.3390/biom15060773] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/30/2025] [Revised: 05/13/2025] [Accepted: 05/22/2025] [Indexed: 06/28/2025]  Open
43
Li N, Xu J, Liu B, Elango J, Wu W. Highly Soluble Mussel Foot Protein Enhances Antioxidant Defense and Cytoprotection via PI3K/Akt and Nrf2/HO-1 Pathways. Antioxidants (Basel) 2025;14:644. [PMID: 40563279 DOI: 10.3390/antiox14060644] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/17/2025] [Revised: 05/22/2025] [Accepted: 05/26/2025] [Indexed: 06/28/2025]  Open
44
Ungureanu D, Marc G, Tiperciuc B, Moldovan C, Ionuț I, Stana A, Oniga I, Vlase L, Pîrnău A, Oniga O. Novel 3,4-Dihydroxyphenyl-Thiazole-Coumarin Hybrid Compounds: Synthesis, In Silico and In Vitro Evaluation of Their Antioxidant Activity. Antioxidants (Basel) 2025;14:636. [PMID: 40563271 DOI: 10.3390/antiox14060636] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/18/2025] [Revised: 05/22/2025] [Accepted: 05/23/2025] [Indexed: 06/28/2025]  Open
45
Stojanović TD, Rakić MR, Ćosić MV, Oalđe Pavlović MM, Sabovljević AD, Sabovljević MS, Božić BĐ, Božić Nedeljković BĐ, Vujičić MM, Lunić TM. Moss Extracts as Natural Neuroprotective Agents: Mitigating LPS-Induced Neuroinflammation and Microglial Activation. Cells 2025;14:780. [PMID: 40497956 PMCID: PMC12153916 DOI: 10.3390/cells14110780] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/14/2025] [Revised: 05/20/2025] [Accepted: 05/23/2025] [Indexed: 06/19/2025]  Open
46
Wu D, Zhang S, Wu Y, Bi X, Zhou Y, Wu W. Sulforaphane downregulates mitochondrial TIGAR via inhibiting mitochondrial transmembrane assembly and LONP1/CASP3 axis causing apoptosis. Biochem Biophys Res Commun 2025;760:151689. [PMID: 40157290 DOI: 10.1016/j.bbrc.2025.151689] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/27/2025] [Revised: 03/17/2025] [Accepted: 03/23/2025] [Indexed: 04/01/2025]
47
Chen Y, Tian Y, Guan B, Chang Y, Yan X, Song Q, Chen W, Chen L, Li W, Mao W, Zhang Y, Chen C, Li S. Morinda officinalis oligosaccharides attenuate mitochondria-associated ferroptosis via the NOX4/mitoGPX4 pathway in myocardial ischemia‒reperfusion injury. Front Cell Dev Biol 2025;13:1605513. [PMID: 40491951 PMCID: PMC12146387 DOI: 10.3389/fcell.2025.1605513] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/03/2025] [Accepted: 05/06/2025] [Indexed: 06/11/2025]  Open
48
Liu P, Chen Y. Integrative Analysis of EPHX4 as a Novel Prognostic and Diagnostic Biomarker in Lung Adenocarcinoma. Int J Mol Sci 2025;26:5095. [PMID: 40507905 PMCID: PMC12154108 DOI: 10.3390/ijms26115095] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/01/2025] [Revised: 05/22/2025] [Accepted: 05/23/2025] [Indexed: 06/16/2025]  Open
49
Caller T, Moore KJ, Lehmann LH, Wu SM, Leor J. Insights Into Heart-Tumor Interactions in Heart Failure. Circ Res 2025;136:1262-1285. [PMID: 40403117 DOI: 10.1161/circresaha.124.325490] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/23/2024] [Revised: 02/10/2025] [Accepted: 02/27/2025] [Indexed: 05/24/2025]
50
Liu B, Zhou F, Shi B, Yan Y, Wang Y, Wang J, Lang Y, Xu S. Peptide YY fragment PYY1-36 disrupts mitochondrial biogenesis via RBM43-dependent PGC-1α translation inhibition. Invest New Drugs 2025:10.1007/s10637-025-01545-4. [PMID: 40404898 DOI: 10.1007/s10637-025-01545-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/10/2025] [Accepted: 05/08/2025] [Indexed: 05/24/2025]
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