Effectiveness of mesenchymal stem cell-derived extracellular vesicles therapy for Parkinson’s disease: A systematic review of preclinical studies

Table 1 Description of the trim-and-fill method process for the rotarod test

Method	Pooled Est	95%CI		Asymptotic		No. of studies
		Lower	Upper	z value	P value
Fixed	0.112	0.078	0.161	-11.835	0.000	12
Random	0.081	0.040	0.162	-7.094	0.000

Test for heterogeneity: Q = 38.328 on 11 degrees of freedom (P = 0.000). Moment-based estimate of between studies variance = 1.038. CI: Confidence interval.