Basic Study
Copyright ©The Author(s) 2024.
World J Stem Cells. Jun 26, 2024; 16(6): 708-727
Published online Jun 26, 2024. doi: 10.4252/wjsc.v16.i6.708
Table 1 Clinical data of patients with and without pelvic organ prolapse
Parameters
Non-POP
POP
P value
Age (yr), mean ± SD52.5 ± 7.18457.9 ± 11.03NS1
BMI (kg/m2), mean ± SD24.57 ± 3.65523.3 ± 2.943NS1
Parity (n), mean ± SD1.8 ± 0.42161.2 ± 0.4206NS2
Menopause, n (%)70%50%NS3
POP stage, median (range)03 (3-4)< 0.0001
Table 2 The primers sequences utilized in this study
Gene
Primer sequences
Col 1A1 FWGTGCGATGACGTGATCTGTGA
Col 1A1 RVCGGTGGTTTCTTGGTCGGT
Col 1A2 FWTTGAAGGAGGATGTTCCCATCT
Col 1A2 RVACAGACACATATTTGGCATGGTT
Col 3A1 FWTTGAAGGAGGATGTTCCCATCT
Col 3A1 RVACAGACACATATTTGGCATGGTT
MMP1 FWCTCTGGAGTAATGTCACACCTCT
MMP1 RVTGTTGGTCCACCTTTCATCTTC
TIMP1 FWAGAGTGTCTGCGGATACTTCC
TIMP1 RVCCAACAGTGTAGGTCTTGGTG
Elastin FWGCAGGAGTTAAGCCCAAGG
Elastin RVTGTAGGGCAGTCCATAGCCA
LOX FWCGGCGGAGGAAAACTGTCT
LOX RVTCGGCTGGGTAAGAAATCTGA
GAPDH FWTGACATCAAGAAGGTGGTGAAGCAG
GAPDH RVGTGTCGCTGTTGAAGTCAGAGGAG