Regenerative potential of mouse embryonic stem cell-derived PDGFRα+ cardiac lineage committed cells in infarcted myocardium

Table 1 Echocardiographic parameters of Control, MI, MI+PDGFRα⁺ CLCs, and MI+αMHC⁺ CMs groups

Group	LVIDd	LVIDs	IVSd	IVSs	LVPWd	LVPWs	LVEDV	LVESV	LVSV	LVEF	FS
	(mm)	(mm)	(mm)	(mm)	(mm)	(mm)	(mL)	(mL)	(mL)	(%)	(%)
Control	4.46 ± 0.23	3.14 ± 0.14	0.76 ± 0.07	1.08 ± 0.05	0.76 ± 0.10	1.11 ± 0.07	0.22 ± 0.04	0.08 ± 0.01	0.14 ± 0.03	62.7 ± 2.52	29.2 ± 1.72
(n = 7)
MI	5.57 ± 0.60	5.09 ± 0.54	0.67 ± 0.04	0.71 ± 0.07	0.74 ± 0.09	1.03 ± 0.17	0.42 ± 0.14	0.32 ± 0.10	0.10 ± 0.03	22.5 ± 2.91	8.61 ± 1.12
(n = 7)
MI+PDGFRα+ CLCs	4.96 ± 0.38	3.92b ± 0.54	0.68 ± 0.10	0.87 ± 0.27	0.68 ± 0.06	0.99 ± 0.13	0.21b ± 0.14	0.12b ± 0.08	0.09 ± 0.06	42.4b ± 4.38	18.1b ± 2.54
(n = 7)
MI+αMHC+ CMs	5.15 ± 0.56	4.38 ± 0.60	0.65 ± 0.04	0.69 ± 0.04	0.74 ± 0.07	1.08 ± 0.12	0.28a ± 0.14	0.18b ± 0.10	0.10 ± 0.05	38.1b ± 6.86	15.8b ± 4.79
(n = 7)

^aP < 0.05 vs MI.

^bP < 0.01 vs MI.

The parameters present as mean ± SD. LVIDd: Left ventricular internal diameter diastole; LVIDs: Left ventricular internal dimension systole; IVSd: Interventricular septal diastole; IVSs: Interventricular septal systole; LVPWd: Left ventricular posterior wall diameter diastole; LVPWs: Left ventricular posterior wall diameter systole; LVEDV: Left ventricular end diastolic volume; LVESV: Left ventricular end systolic volume; LVSV: Left ventricular stroke volume; LVEF: Left ventricular ejection fraction; FS: Fractional shortening; CLCs: Cardiac lineage-committed cells; CMs: Cardiomyocytes; MI: Myocardial infarction.