Telomere dynamics in induced pluripotent stem cells: Potentials for human disease modeling

doi:10.4252/wjsc.v3.i10.89

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Oct 26, 2011 (publication date) through Nov 30, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2011; 3(10): 89-95
Published online Oct 26, 2011. doi: 10.4252/wjsc.v3.i10.89

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Figure 1 Telomerase enzyme. Simplified illustration of the telomerase enzyme showing its main components: hTERT, hTERC, Dyskerin, NOP10, NHP2, GAR1, and TCAB1. Functional regions of the hTERC RNA (template, pseudoknot, CR4-CR5, Box H/ACA, and CR7) are indicated. Mutations in hTERT, hTERC, TCAB1, NOP10 or Dyskerin have been shown to be associated with a severe form of human bone-marrow deficiency known as dyskeratosis congenita.

Citation: Ly H. Telomere dynamics in induced pluripotent stem cells: Potentials for human disease modeling. World J Stem Cells 2011; 3(10): 89-95
URL: https://www.wjgnet.com/1948-0210/full/v3/i10/89.htm
DOI: https://dx.doi.org/10.4252/wjsc.v3.i10.89