DNA methylation and demethylation link the properties of mesenchymal stem cells: Regeneration and immunomodulation

doi:10.4252/wjsc.v12.i5.351

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. May 26, 2020; 12(5): 351-358
Published online May 26, 2020. doi: 10.4252/wjsc.v12.i5.351

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Figure 1 Hypomethylation of specific genes in mesenchymal stem cells drives multi-lineage differentiation and tissue regeneration. MSCs: Mesenchymal stem cells.

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Figure 2 TET-mediated demethylation functions in regulatory T cell differentiation and mesenchymal stem cell-induced T cell apoptosis. MSCs: Mesenchymal stem cells; Treg: Regulatory T cells.

Citation: Xin TY, Yu TT, Yang RL. DNA methylation and demethylation link the properties of mesenchymal stem cells: Regeneration and immunomodulation. World J Stem Cells 2020; 12(5): 351-358
URL: https://www.wjgnet.com/1948-0210/full/v12/i5/351.htm
DOI: https://dx.doi.org/10.4252/wjsc.v12.i5.351