Review
Copyright ©The Author(s) 2019.
World J Stem Cells. Jul 26, 2019; 11(7): 398-420
Published online Jul 26, 2019. doi: 10.4252/wjsc.v11.i7.398
Figure 1
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Figure 1 Targeting Wnt, hedgehog, notch, bone morphogenetic protein, B-cell-specific Moloney murine leukemia virus integration site, PI3K/Akt, and signal transducers and activators of transcription signaling pathways and the characteristics of cancer stem cells. Bmi: B-cell-specific Moloney murine leukemia virus integration site; STAT: Signal transducers and activators of transcription; BMP: Bone morphogenetic protein.
Figure 2
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Figure 2 Chemical structure of agents targeting the Wnt signaling pathway in clinical trials.
Figure 3
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Figure 3 Chemical structure of agents targeting the Notch signaling pathway in clinical trials.
Figure 4
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Figure 4 Chemical structure of agents targeting the Smoothened protein in clinical development.
Figure 5
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Figure 5 Chemical structure of napabucasin and GDC-0084.