Copyright ©The Author(s) 2019.
World J Stem Cells. Nov 26, 2019; 11(11): 982-989
Published online Nov 26, 2019. doi: 10.4252/wjsc.v11.i11.982
Figure 1
Figure 1 Schematic illustration for neurogenesis of neural stem cell (NSC) grafts within a host hippocampal tissue, showing the difference in relative proportions for neuronal (yellow) vs glial (purple) NSC lineage between physiological environment (a) and the post-ischemic milieu (tissue subjected to oxygen-glucose deprivation) (b) at an earlier time-window – first 2 weeks after engraftment into organotypic hippocampal tissue. NSC are fetal progenitors isolated from mouse hippocampus grafted into organotypic hippocampal slices for monitoring the time-dependent NSC neurogenesis within a host tissue.