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World J Stem Cells. Dec 31, 2009; 1(1): 43-48
Published online Dec 31, 2009. doi: 10.4252/wjsc.v1.i1.43
Published online Dec 31, 2009. doi: 10.4252/wjsc.v1.i1.43
The famous versus the inconvenient - or the dawn and the rise of 3D-culture systems
Brigitte Altmann, Alexander Welle, Stefan Giselbrecht, Eric Gottwald, Institute for Biological Interfaces, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany
Roman Truckenmüller, University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Tissue Regeneration, Drienerlolaan 5, 7522 NB Enschede, The Netherlands
Author contributions: Altmann B performed bioreactor experiments and wrote the draft of the manuscript; Giselbrecht S and Truckenmüller R manufactured the KITChips and contributed substantially to the chapter 3D-matrices; Welle A and Giselbrecht S performed the surface modifications of the KITChips; Welle A performed the experiments with polylactic-co-glycolic acid and contributed substantially to the chapter 3D-matrices; Gottwald E performed bioreactor experiments and was responsible for the concept and final approval of the manuscript.
Supported by The European Union Grant STREP NMP3-CT-29005-013811 (to Welle A); the Bundesministerium für Bildung und Forschung Grant 03ZIK-465 (to Altmann B), Germany
Correspondence to: Dr. Eric Gottwald, Institute for Biological Interfaces, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany. eric.gottwald@kit.edu
Telephone: +49-7247-822504 Fax: +49-7247-825546
Received: November 28, 2009
Revised: December 9, 2009
Accepted: December 16, 2009
Published online: December 31, 2009
Revised: December 9, 2009
Accepted: December 16, 2009
Published online: December 31, 2009
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