临床研究
Copyright ©The Author(s) 2022.
世界华人消化杂志. 2022-06-28; 30(12): 521-528
在线出版 2022-06-28. doi: 10.11569/wcjd.v30.i12.521
表1 两组疗效比较n(%)
组别例数显效有效无效
实验组3325(75.76)7(21.21)1(3.03)
对照组3314(42.42)16(48.48)3(9.09)
u2.378
P0.017
表2 两组炎症指标比较(mean±SD)
时间组别例数CRP(mg/L)PCT(ng/mL)WBC(×109/L)TNF-α(ng/mL)
治疗前实验组3316.25±5.382.89±0.8414.67±3.2952.38±12.69
对照组3315.74±4.972.93±0.9113.82±3.5050.84±10.22
t0.4000.1861.0170.543
P0.6910.8530.3130.589
治疗3 d后实验组3311.06±3.81a1.53±0.47a10.09±1.05a32.26±9.50a
对照组3313.22±3.26a1.86±0.51a11.54±1.28a41.39±10.07a
t2.4752.7335.0313.789
P0.0160.008<0.001<0.001
治疗5 d后实验组337.17±1.93ab0.40±0.13ab7.28±0.97ab24.39±5.88ab
对照组3310.35±2.24ab0.86±0.24ab9.33±0.84ab30.95±7.27ab
t6.1789.6819.1784.030
P<0.001<0.001<0.001<0.001
表3 两组IL-4/IL-13/STAT6信号通路比较(mean±SD)
时间组别例数IL-4 mRNAIL-13 mRNASTAT6 mRNA
治疗前实验组333.58±1.125.75±1.824.88±1.50
对照组333.29±1.006.03±1.944.65±1.48
t1.1100.6050.627
P0.2710.5480.533
治疗3 d后实验组332.39±0.85a3.11±0.97a2.03±0.62a
对照组332.86±0.92a4.28±1.23a2.59±0.73a
t2.1564.2913.359
P0.035<0.001<0.001
治疗5 d后实验组331.53±0.26ab1.97±0.84ab1.26±0.33ab
对照组332.26±0.34ab2.79±0.90ab1.84±0.56ab
t9.7963.8265.126
P<0.001<0.001<0.001
表4 两组感染切口恢复情况比较(mean±SD)
组别例数换药次数(次)红肿痛缓解时间(d)病原菌培养转阴时间(d)住院时间(d)
实验组338.02±2.154.19±1.246.48±0.8310.18±2.33
对照组3310.47±2.285.56±1.707.59±0.6212.67±2.19
t4.4913.7406.1554.473
P<0.001<0.001<0.001<0.001
表5 两组VSS评分比较(mean±SD, 分)
组别例数色泽血管柔软性厚度疼痛
实验组330.64±0.200.31±0.100.84±0.230.40±0.120.24±0.06
对照组330.95±0.260.53±0.111.09±0.210.62±0.150.39±0.13
t5.4298.5014.6116.5796.018
P<0.001<0.001<0.001<0.001<0.001

引文著录: 马柏英, 傅旭堂, 陈芃芃, 李肃. 红外线局部照射联合皮肤再生医疗技术治疗开腹胃肠外科术后切口感染效果及对IL-4/IL-13/STAT6信号通路影响. 世界华人消化杂志 2022; 30(12): 521-528