临床研究
Copyright ©The Author(s) 2022.
世界华人消化杂志. 2022-06-08; 30(11): 484-490
在线出版 2022-06-08. doi: 10.11569/wcjd.v30.i11.484
表1 2组一般资料比较
项目观察组(n = 37)对照组(n = 37)t/χ2P
性别(男/女)20/1718/190.2160.642
年龄(岁)35-76(59.89±5.10)41-85(61.23±6.65)0.8320.398
乙型肝炎病史
22(59.46)25(67.57)0.5250.469
15(40.54)12(32.43)
肿瘤直径(cm)3.1-9.5(7.42±1.06)3.5-10.2(7.32±1.12)0.3950.694
临床分期
Ⅱ期20(54.05)16(43.24)0.8660.352
Ⅲ期17(45.95)11(29.73)
肿瘤个数(个)1-4(2.02±0.41)1-3(2.09±0.44)0.7080.481
表2 两组循环功能指标水平比较(mean±SD)
循环指标组别例数T0T1T2T3T4
MAP(mmHg)A组3793.71±18.2581.37±15.62ab83.25±13.14ab86.74±12.39ab93.06±10.12
B组3792.14±15.6969.84±9.41a75.16±15.69a78.52±9.31a94.25±10.26
t0.3976.1612.4053.2260.502
P0.693<0.0010.0190.0020.617
HR(次/min)A组3792.27±24.1681.19±10.25ab82.41±10.98ab85.27±12.31ab95.49±12.49
B组3791.97±26.3175.26±9.21a76.03±11.02a78.02±10.29a99.02±15.87
t0.0512.6182.4952.6741.063
P0.9590.0110.0150.0080.291
表3 两组脑功能状态指数比较(mean±SD)
脑功能状态组别例数T0T1T2T3T4
小波指数A组3796.37±20.3758.46±12.41ab65.31±15.61ab74.12±16.37ab87.14±15.23
B组3795.84±19.2575.21±15.69a78.69±20.45a83.12±20.83a94.02±18.41
t0.1155.0933.1642.0661.852
P0.909<0.0010.0020.0420.123
焦虑指数A组3714.12±3.257.13±1.25ab19.41±3.28ab22.17±4.25ab14.83±3.14
B组3713.58±3.0911.89±2.04a24.13±5.06a28.63±6.12a14.25±4.29
t0.68512.1024.7615.2740.664
P0.512<0.001<0.001<0.0010.509
舒适指数A组3711.85±3.027.25±2.07ab25.41±4.26ab31.41±8.25ab12.94±4.02a
B组3712.07±4.0110.38±2.05a40.13±8.31a47.83±10.37a12.63±5.69
t0.7566.5839.5887.5370.271
P0.432<0.001<0.001<0.0010.787
表4 两组丙泊酚用量及麻醉苏醒时间比较(mean±SD)
组别例数丙泊酚用量(mg/min)麻醉苏醒时间(min)
A组3713.12±3.263.25±1.05
B组3713.59±4.042.27±0.74
t0.5514.641
P0.584<0.001
表5 两组术后VAS评分比较(mean±SD, 分)
组别例数术后30 min术后3 h差值
A组372.41±0.30ab3.25±0.32ab0.84±0.24b
B组372.78±0.49a4.21±0.57a1.43±0.41
t3.9178.9337.554
P<0.001<0.001<0.001
表6 两组手术前后MMSE评分比较(mean±SD, 分)
组别例数术前1 d术后第1 d术后第2 d
A组3728.63±1.6526.89±2.31ab27.12±1.78a
B组3729.21±1.5825.24±2.49a27.31±2.04a
t1.5442.9550.427
P0.1270.0040.671
表7 两组不良反应发生率比较[n(%)]
组别例数恶心、呕吐低血压心动过缓体动
A组375(13.51)0(0.00)0(0.00)15(40.54)
B组377(18.92)1(2.70)1(2.70)28(75.68)
χ20.398-0.0009.382
P0.5281.0001.0000.002

引文著录: 丁雯, 胡壮文. 超声引导下经皮微波消融术中丙泊酚不同输注方法对肝癌患者脑功能状态指数及循环功能的影响. 世界华人消化杂志 2022; 30(11): 484-490