胃黏膜上皮内瘤变患者653例的临床病理特点分析

表1 653例GIN患者的一般特征、内镜下表现及病理特点

	LGIN (536例)	HGIN (117例)	χ2	P值
性别			1.082	0.298
男	363 (55.59%)	85 (13.02%)
女	173 (26.49%)	32 (4.90%)
年龄a			22.537	<0.001
<49	93 (14.24%)	6 (0.92%)
49-59	177 (27.11%)	32 (4.90%)
≥60	266 (40.74%)	85 (13.02%)
病变部位a			29.562	<0.001
胃角	57 (10.63%)	14 (11.97%)
胃体	14 (2.61%)	14 (11.97%)
胃窦	332(61.94%)	49 (41.88%)
多部位	133(24.81%)	40 (34.19%)
病变分型			2.241	0.134
0-Ⅱa	452 (84.33%)	92 (78.63%)
其它0型病变	84 (15.67%)	25 (21.37%)
病变大小a			68.673	<0.001
<1 cm	294 (54.85%)	15 (12.82%)
1 cm-2 cm	186 (34.70%)	75 (64.10%)
>2 cm	56 (10.45%)	27 (23.08%)
萎缩a			16.968	<0.001
萎缩	396 (73.88%)	64 (54.70%)
非萎缩	140 (26.12%)	53 (45.30%)
肠化a			41.509	<0.001
肠化	428 (79.85%)	60 (51.28%)
非肠化	108 (20.15%)	57 (48.72%)
H. pylori			1.959	0.162
阳性	140 (26.12%)	38 (32.48%)
阴性	396 (73.88%)	79 (67.52%)

LGIN组 vs HGIN组,

^aP<0.05. GIN: 胃黏膜上皮内瘤变; LGIN: 胃黏膜低级别上皮内瘤变; HGIN: 胃黏膜高级别上皮内瘤变. H. pylori: 幽门螺杆菌.

表2 不同年龄组间肠化、萎缩在LGIN、HGIN间相关关系的统计

年龄组 (岁)	LGIN(536例)	HGIN(117例)	χ2	P值	LGIN(536例)	HGIN(117例)	χ2	P值
	萎缩				肠化
20-39	18 (48.65%)	1 (100%)	1.03	0.311	17 (45.95%)	0 (0.00%)	41.51	<0.001
40-49	34 (60.71%)	5 (100%)	3.07	0.080	38 (67.86%)	3 (60.00%)	0.83	0.362
50-59	129 (72.88%)	14 (53.85%)	3.95	0.047	146 (82.49%)	6 (23.08%)	0.13	0.720
60-69	142 (81.14%)	17 (53.13%)	11.92	0.001	149 (85.14%)	11 (34.38%)	42.53	<0.001
70-79	55 (84.62%)	18 (50.00%)	13.86	<0.001	57 (87.69%)	25 (69.44%)	39.73	<0.001
>80	18 (69.23%)	9 (52.94%)	1.167	0.28	21 (80.77%)	15 (88.24%)	5.05	0.025

LGIN组 vs HGIN组. GIN: 胃黏膜上皮内瘤变; LGIN: 胃黏膜低级别上皮内瘤变; HGIN: 胃黏膜高级别上皮内瘤变.