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©The Author(s) 2021.
世界华人消化杂志. 2021-08-08; 29(15): 873-879
在线出版 2021-08-08. doi: 10.11569/wcjd.v29.i15.873
在线出版 2021-08-08. doi: 10.11569/wcjd.v29.i15.873
表1 NRBP组与LRBP组基线资料比较
| NRBP(n = 41) | LRBP(n = 135) | 检验值 | P值 | |
| 年龄[岁, M (P25, P75)] | 37 (31.5, 45) | 42 (32, 52) | -1.259 | 0.208 |
| 性别(男, %) | 33 (80.5%) | 88 (65,2%) | 3.428 | 0.064 |
| BMI[kg/m2, M (P25, P75)] | 26.13 (23.80, 29.32) | 26.82 (24.42, 28.85) | -0.672 | 0.502 |
| 吸烟史(n, %) | 19 (46.3%) | 37 (27.4%) | 5.197 | 0.023 |
| 饮酒史(n, %) | 18 (43.9%) | 39 (28.9%) | 3.237 | 0.072 |
| 高血压(n, %) | 9 (22.0%) | 20 (14.8%) | 1.164 | 0.281 |
| 糖尿病(n, %) | 10 (24.4%) | 30 (22.2%) | 0.084 | 0.772 |
| 高脂血症(n, %) | 23 (56.1%) | 74 (54.4%) | 0.036 | 0.849 |
| 病因(n, %) | 1.134 | 0.769 | ||
| 胆源性 | 16 (39.0%) | 58 (43.0%) | ||
| 高甘油三酯血症性 | 23 (56.1%) | 71 (52.6%) | ||
| 酒精性 | 1 (2.4%) | 1 (0.7%) | ||
| 其他 | 1 (1%) | 5 (3.7%) |
表2 NRBP组与LRBP组严重程度和预后比较
| NRBP(n = 41) | LRBP(n = 135) | 检验值 | P值 | |
| RAC分型(n, %) | 12.059 | 0.002 | ||
| MAP | 16 (39.0%) | 21 (15.6%) | ||
| MSAP | 12 (29.3%) | 72 (53.3%) | ||
| SAP | 13 (31.7%) | 42 (31.1%) | ||
| 局部并发症(n, %) | ||||
| 急性胰周液体积聚 | 4 (9.8%) | 19 (14.1%) | 0.516 | 0.472 |
| 急性坏死组织积聚 | 21 (51.2%) | 95 (70.4%) | 5.133 | 0.023 |
| 假性囊肿 | 0 | 0 | ||
| 包裹性坏死 | 0 | 0 | ||
| 器官衰竭(n, %) | ||||
| ARDS | 13 (31.7%) | 49 (36.3%) | 0.290 | 0.590 |
| AKI | 10 (24.4%) | 24 (17.8%) | 0.882 | 0.348 |
| Shock | 5 (12.2) | 12 (8.9%) | 0.394 | 0.550 |
| 脓毒症(n, %) | 3 (7.3%) | 8 (5.9) | 0.104 | 0.720 |
| WBC[×109/L, M (P25, P75)] | 11.40 (8.45, 14.70) | 10.40 (7.61, 13.40) | -2.011 | 0.044 |
| CRP (mg/L, mean±SD ) | 143.22±12.47 | 175.93±7.18 | -2.187 | 0.030 |
| PCT [μg/L, M (P25, P75)] | 0.49 (0.16, 3.66) | 0.52 (0.16, 1.75) | -0.580 | 0.562 |
| 死亡(n, %) | 1 (2.4%) | 8 (5.9%) | 0.788 | 0.687 |
| 住院时长[天, M (P25, P75)] | 5 (3.5, 17) | 7 (4, 11) | -0.481 | 0.631 |
| 总费用[万元, M (P25, P75)] | 3.40 (2.36, 16.49) | 3.69 (2.55, 8.21) | -0.131 | 0.896 |
表3 局部并发症的危险因素分析
| 无局部并发症(n = 37) | 有局部并发症(n = 139) | 检验值 | P值 | OR (95%CI) | P值 | |
| 年龄[岁, M (P25, P75)] | 44 (34.5, 51.5) | 40 (32, 50) | -1.286 | 0.198 | 0.983 (0.956, 1.011) | 0.228 |
| 性别(男, %) | 28 (75.7%) | 93 (66.9%) | 1.046 | 0.306 | 0.65 (0.283, 1.490) | 0.309 |
| BMI[kg/m2, M (P25, P75)] | 25.54 (23.36, 27.68) | 26.82 (24.56, 29.39) | -1.664 | 0.096 | 1.113 (0.984, 1.259) | 0.089 |
| 吸烟史(n, %) | 14 (37.8%) | 42 (30.2%) | 0.783 | 0.376 | 0.711 (0.334, 1.516) | 0.378 |
| 饮酒史(n, %) | 13 (35.1%) | 44 (31.7%) | 0.162 | 0.688 | 0.855 (0.398, 1.835) | 0.688 |
| 高血压(n, %) | 4 (10.8%) | 25 (18.0%) | 1.093 | 0.296 | 1.809 (0.588, 5.569) | 0.301 |
| 糖尿病(n, %) | 9 (24.3%) | 31 (22.3%) | 0.068 | 0.794 | 0.893 (0.381, 2.091) | 0.794 |
| 高脂血症(n, %) | 15 (40.5%) | 81 (58.3%) | 3.706 | 0.054 | 2.048 (0.979, 4.284) | 0.057 |
| 病因(n, %) | 4.959 | 0.173 | ||||
| 胆源性 | 18 (48.6%) | 56 (40.3%) | 3.111 (0.576, 16.795) | 0.187 | ||
| 高甘油三酯血症性 | 16 (43.2%) | 78 (56.1%) | 4.875 (0.901, 26.375) | 0.066 | ||
| 酒精性 | 0 | 2 (1.4%) | 1 | |||
| 特发性 | 3 (8.1%) | 3 (2.2%) | 1 | 0.265 | ||
| WBC[×109/L, M (P25, P75)] | 10.8 (8.38, 14.00) | 10.60 (7.80, 13.90) | -0.719 | 0.472 | 1.002 (0.937,1.072) | 0.951 |
| CRP (mg/L, mean±SD) | 115.81±12.23 | 183.31±6.79 | -4.687 | 0.000 | 1.011 (1.006, 1.016) | 0.000 |
| PCT[μg/L, M (P25, P75)] | 0.29 (0.10, 0.75) | 0.65 (0.18, 3.42) | -3.007 | 0.003 | 1.017 (0.965, 1.293) | 0.137 |
| RBP[mg/L, M (P25, P75)] | 24.00 (15.00, 27.50) | 12.00 (9.00, 22.00) | -3.881 | 0.000 | 0.935 (90.899, 0.972) | 0.001 |
| RBP降低(n, %) | 21 (56.8%) | 114 (82.0%) | 10.433 | 0.001 | 3.474 (1.591, 7.589) | 0.002 |
引文著录: 董小武, 魏梅, 马楠, 陆蓥蓥, 谢晓纯, 施笑蕾, 董杰, 马孝杰, 李百强, 童智慧, 李维勤. 循环视黄醇结合蛋白是急性胰腺炎局部并发症的独立危险因素. 世界华人消化杂志 2021; 29(15): 873-879