临床研究
Copyright ©The Author(s) 2020.
世界华人消化杂志. 2020-11-08; 28(21): 1068-1075
在线出版 2020-11-08. doi: 10.11569/wcjd.v28.i21.1068
表1 大肠息肉病理分型与一般情况比较
项目n腺瘤性息肉
非腺瘤性息肉
腺瘤总数腺瘤发生率(%)Pχ2
管状腺瘤绒毛状腺瘤混合状腺瘤炎性息肉增生性息肉
性别0.03714.3301
166651233164011066.27
1344681915467354.48
民族0.38510.7551
1194072212386957.98
181711330194811462.98
职业0.01019.2031
体力6419396273148.44
半体力1063581811346157.550.24821.3342
脑力1305792514259170.000.00438.5493
年龄(岁)0.000117.3321
20-4055191114202138.18
41-601063772013296460.380.00727.1582
61-801395512314379870.500.000317.3603
直径(cm)0.006110.1371
1.0≤1365351211557051.47
1.1-1.912548102613288467.200.1026.6622
≥2.03910514732974.360.01136.4633
山田分型0.000140.3421
111371721454540.54
5120196153058.820.03024.6982
4619394113167.390.00239.3883
92351527-157783.700.000439.0684
息肉数量0.04114.1761
单发14245132012527854.93
多发15866732193410566.46
发病部位0.000143.2971
直肠923561810235964.13
左半结肠12461112411179677.420.03224.6022
右半结肠4810365241939.580.00637.7033
回盲部365-4522925.000.000415.9104
低级别内瘤变14599640--18361.00--
高级别内瘤变38121412
表2 中医证型与内镜下息肉形态分布特征, n (%)
中医证型n内镜下息肉形态特征
是否带蒂
黏膜形态
无蒂亚蒂有蒂光滑形分叶形糜烂形颗粒形混合形
脾虚湿蕴证7634 (44.74)25 (32.89)17 (22.37)26 (34.21)19 (25.00)16 (21.05)8 (10.53)7 (9.21)
气滞血瘀证4310 (23.26)14 (32.56)19 (44.19)6 (13.95)14 (32.56)4 (9.30)17 (39.53)2 (4.65)
血虚肠燥证265 (19.23)9 (34.62)12 (46.15)3 (11.54)1 (3.85)3 (11.54)12 (46.15)7 (26.92)
寒湿阻滞证5426 (48.15)17 (31.48)11 (20.37)22 (40.74)16 (29.63)7 (12.96)4 (7.41)5 (9.26)
大肠湿热证6528 (43.08)22 (33.85)15 (23.08)25 (38.46)18 (27.69)9 (13.85)5 (7.69)8 (12.31)
肝郁气滞证368 (22.22)10 (27.78)18 (50.00)7 (19.44)12 (33.33)-15 (41.67)2 (5.56)
合计300111979211674443927
χ2 = 24.349 , P = 0.007χ2 = 74.686, P = 0.000
表3 中医证型与内镜下息肉大小、数目、部位分布特征, n (%)
中医证型n内镜下息肉大小、数目、部位特征
<1 cm1-2 cm>2 cm单发性多发性回盲部右半结肠左半结肠直肠
脾虚湿蕴证7640 (52.63)24 (31.58)12 (15.79)27 (35.53)49 (64.47)10 (13.16)11 (14.47)30 (39.47)25 (32.89)
气滞血瘀证4314 (32.56)23 (53.49)6 (13.95)28 (65.12)15 (34.88)5 (11.63)9 (20.93)16 (37.21)13 (30.23)
血虚肠燥证267 (26.92)16 (61.54)3 (11.54)16 (61.54)10 (38.46)2 (7.69)4 (15.38)12 (46.15)8 (30.77)
寒湿阻滞证5430 (55.56)18 (33.33)6 (11.11)20 (37.04)34 (62.96)7 (12.96)11 (20.37)22 (40.74)14 (25.92)
大肠湿热证6532 (49.23)25 (38.46)8 (12.31)29 (44.62)36 (55.38)11 (16.92)8 (12.31)26 (40.00)20 (30.77)
肝郁气滞证3613 (36.11)19 (52.78)4 (11.11)22 (61.11)14 (38.89)1 (2.78)5 (13.89)18 (50.00)12 (33.33)
总计300136 (45.33)125 (41.67)39 (13.00)142 (47.33)158 (52.67)36 (12.00)48 (16.00)124(41.33)92 (30.67)
χ2 = 15.211, P = 0.125χ2 = 17.040, P = 0.004χ2 = 8.145, P = 0.918
表4 中医证型与病理分型分布特征, n (%)
中医证型n病理分型
腺瘤性息肉
非腺瘤性息肉
管状腺瘤绒毛状腺瘤混合状腺瘤炎性息肉增生性息肉
脾虚湿蕴证7630 (39.47)5 (6.58)10 (13.16)7 (9.21)24 (31.58)χ2 = 14.271 P = 0.014
气滞血瘀证436 (13.95)3 (6.98)7 (16.28)8 (18.60)19 (44.19)
血虚肠燥证264 (15.38)-5 (19.23)3 (11.54)14 (53.85)
寒湿阻滞证5423 (42.59)5 (9.26)6 (11.11)4 (7.41)16 (29.63)
大肠湿热证6526 (40.00)6 (9.23)7 (10.77)7 (10.77)19 (29.23)
肝郁气滞证361 (30.56)1 (2.78)3 (8.33)8 (22.22)13 (36.11)
总计300100 (33.33)20 (6.67)38 (12.67)41 (13.67)101 (33.67)

引文著录: 赵红波, 吴晓晶, 杨云, 葛志明, 王宏伟. 大肠息肉内镜下形态学特点、病理分型与中医证型的相关性. 世界华人消化杂志 2020; 28(21): 1068-1075