临床研究
Copyright ©The Author(s) 2019.
世界华人消化杂志. 2019-08-08; 27(15): 936-942
在线出版 2019-08-08. doi: 10.11569/wcjd.v27.i15.936
表1 重度反流性食管炎影响因素的单因素Logistic回归分析
变量BOR95%CIP
性别(男)1.4764.3342.5507.3670.000
BMI0.1601.1731.0971.2540.000
吸烟史0.9272.5281.6053.9810.000
高密度脂蛋白胆固醇-0.7160.4890.2480.9640.039
食管裂孔疝4.05857.8437.609439.7350.000
高血压0.6081.8361.1672.8890.009
高脂血症0.6401.8971.1203.2120.017
表2 轻度反流性食管炎影响因素的单因素Logistic回归分析
变量BOR95%CIP
性别(男)0.4731.6041.1612.2160.004
BMI0.0831.0861.0341.1400.001
吸烟史0.5241.6881.2132.3480.002
甘油三酯0.2271.2541.0751.4630.004
高密度脂蛋白胆固醇-0.5780.5610.3490.9020.017
食管裂孔疝2.85217.3192.299130.4680.006
表3 反流性食管炎影响因素的基线资料表(计数资料)
变量组别N均值标准差均值的标准误P
年龄轻度RE (358)35856.5312.310.650.18
重度RE (117)11758.6612.941.20
对照组 (263)26356.1313.020.80
BMI轻度RE (358)31825.513.690.210.00
重度RE (117)9126.653.540.37
对照组 (263)21024.403.890.27
血糖轻度RE (358)3285.491.690.090.26
重度RE (117)1085.882.460.24
对照组 (263)2415.482.870.19
总胆固醇轻度RE (358)3284.651.050.060.33
重度RE (117)1084.491.040.10
对照组 (263)2444.600.950.06
甘油三脂轻度RE (358)3281.871.480.080.01
重度RE (117)1081.761.190.11
对照组 (263)2441.551.030.07
低密度脂蛋白胆固醇轻度RE (358)3282.700.850.050.74
重度RE (117)1082.630.900.09
对照组 (263)2442.680.830.05
高密度脂蛋白胆固醇轻度RE (358)3281.150.340.020.02
重度RE (117)1081.140.320.03
对照组 (263)2441.230.360.02
表4 反流性食管炎影响因素的基线资料表(计量资料)
变量分类组别P
轻度RE (n = 358)重度RE (n = 117)对照组 (n = 263)
性别 (738)男 (456)225 (62.85%)96 (82.05%)135 (51.33%)0.000
女 (282)133 (37.15%)21 (17.95%)128 (48.67%)
吸烟史 (710)无 (378)170 (50.15%)45 (40.18%)163 (62.93%)0.000
有 (332)169 (49.85%)67 (59.82%)96 (37.07%)
饮酒史 (709)无 (10)6 (1.77%)1 (0.89%)3 (1.16%)0.719
有 (699)333 (98.23%)111 (99.11%)255 (98.84%)
幽门螺杆菌 (738)阴性 (421)216 (60.34%)67 (57.26%)138 (52.47%)0.147
阳性 (317)142 (39.66%)50 (42.74%)125 (47.53%)
食管裂孔疝 (738)无 (694)336 (93.85%)96 (82.05%)262 (99.62%)0.000
有 (44)22 (6.15%)21 (17.95%)1 (0.38%)
既往高血压史 (738)无 (497)243 (67.88%)67 (57.26%)187 (71.10%)0.028
有 (241)115 (32.12%)50 (42.74%)76 (28.90%)
既往糖尿病史 (738)无 (631)306 (85.47%)100 (85.47%)225 (85.55%)1.000
有 (107)52 (14.53%)17 (14.53%)38 (14.45%)
既往高脂血症史 (738)无 (598)291 (81.28%)86 (73.50%)221 (84.03%)0.053
有 (140)67 (18.72%)31 (26.50%)42 (15.97%)
既往脂肪肝病史 (738)无 (673)324 (90.50%)106 (90.60%)243 (92.40%)0.692
有 (65)34 (9.50%)11 (9.40%)20 (7.60%)
表5 反流性食管炎影响因素发多变量Logistic回归分析
组别变量BOR95%CIP
轻度RE性别(男)0.4101.5071.0132.2420.043
BMI0.0701.0721.0161.1320.011
幽门螺杆菌感染-0.4870.6150.4220.8960.011
食管裂孔疝2.47111.8381.55490.1590.017
重度RE性别(男)1.3944.0292.0188.0430.000
BMI0.1291.1371.0541.2260.001
幽门螺杆菌感染-0.4950.6090.3521.0560.078
食管裂孔疝3.51333.5634.195268.5440.001

引文著录: 陈思旭, 尚占民, 郝建宇, 赵前前, 孙皛, 魏玉娜. 基于临床大数据对反流性食管炎相关影响因素的分析. 世界华人消化杂志 2019; 27(15): 936-942