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©The Author(s) 2018.
世界华人消化杂志. 2018-06-28; 26(18): 1095-1101
在线出版 2018-06-28. doi: 10.11569/wcjd.v26.i18.1095
在线出版 2018-06-28. doi: 10.11569/wcjd.v26.i18.1095
表1 各药组对肝纤维化大鼠模型血清AST、ALT、TP、AIb、GLB的影响 (n = 8)
分组 | AST (U/L) | ALT (U/L) | TP (g/L) | AIb (g/L) | GLB (g/L) |
Model | 126.2 ± 29.80 | 49.2 ± 6.43 | 58.8 ± 3.33 | 25.9 ± 1.13 | 33.2 ± 2.36 |
Silybin | 195.5 ± 46.63a | 101.3 ± 28.09a | 51.7 ± 2.64a | 23.8 ± 0.63a | 27.1 ± 1.56a |
HTL | 151.6 ± 44.65 | 76.0 ± 15.76 | 55.3 ± 2.79 | 27.1 ± 1.63e | 27.3 ± 0.43 |
HTM | 125.3 ± 31.26c | 62.8 ± 11.99e | 51.5 ± 2.12 | 25.6 ± 0.79 | 25.9 ± 1.81 |
HTH | 91.5 ± 19.06e | 55.3 ± 10.73e | 58.5 ± 4.44d | 28.8 ± 2.07e | 29.6 ± 2.51 |
HXHYL | 91.8 ± 25.10e | 53.6 ± 11.08e | 55.9 ± 2.20 | 27.7 ± 0.86e | 29.0 ± 1.23 |
HXHYM | 109.6 ± 21.84d | 59.0 ± 9.11e | 55.7 ± 1.68 | 25.8 ± 0.92 | 30.0 ± 1.63 |
HXHYH | 119.7 ± 26.54d | 57.7 ± 11.43e | 54.9 ± 2.25 | 26.1 ± 1.10c | 28.8 ± 1.30 |
FZL | 107.6 ± 23.96e | 53.8 ± 9.15e | 52.4 ± 1.04 | 24.7 ± 1.78 | 26.7 ± 2.04 |
FZM | 143.8 ± 28.09 | 80.4 ± 17.81 | 52.5 ± 3.27 | 25.7 ± 1.25 | 26.4 ± 2.58 |
FZH | 87.2 ± 31.09e | 46.4 ± 10.83e | 52.8 ± 4.14 | 27.7 ± 0.64e | 25.9 ± 2.12 |
HTHXF | 113.2 ± 43.81c | 61.2 ± 23.92e | 53.2 ± 3.42 | 26.9 ± 1.39e | 27.5 ± 3.01 |
ZL | 121.8 ± 29.65d | 65 ± 19.24d | 50.6 ± 2.59 | 25.1 ± 0.66 | 25.4 ± 1.95 |
HTHXF | 105.2 ± 29.85e | 60.6 ± 9.81e | 52.9 ± 1.60 | 26.6 ± 0.43d | 26.1 ± 1.38 |
ZM | 102.8 ± 25.59e | 63.0 ± 12.73e | 56.6 ± 2.70c | 27.5 ± 1.42e | 29.1 ± 2.52 |
HTHXF | |||||
ZH |
表2 各药组对肝纤维化大鼠模型LN、COL4、HA的影响 (n = 8)
分组 | LN | COL4 | HA |
Contrl | 659.4 ± 87.34 | 314.8 ± 24.21 | 10.2 ± 0.79 |
Model | 1021.6 ± 68.75a | 400.8 ± 58.07a | 13.8 ± 1.36a |
Silybin | 587.8 ± 44.10e | 420.0 ± 31.40 | 11.0 ± 1.77 |
HTL | 778.1 ± 123.46d | 328.9 ± 53.50 | 12.8 ± 0.65 |
HTM | 817.9 ± 93.64c | 312.3 ± 63.74c | 12.7 ± 1.78 |
HTH | 630.1 ± 50.82e | 353.3 ± 47.93 | 12.4 ± 1.75 |
HXHYL | 818.7 ± 61.19c | 282.0 ± 27.33e | 13.2 ± 2.22 |
HXHYM | 887.6 ± 94.67 | 348.7 ± 47.40 | 11.6 ± 1.01c |
HXHYH | 754.4 ± 114.4d | 350.1 ± 57.72 | 11.7 ± 1.08 |
FZL | 837.0 ± 103.79c | 336.0 ± 42.03 | 11.7 ± 1.51c |
FZM | 838.2 ± 142.65 | 314.3 ± 59.28c | 12.0 ± 1.11 |
FZH | 695.7 ± 70.64e | 344.6 ± 50.74 | 11.6 ± 1.07 |
HTHXFZL | 801.3 ± 123.81c | 274.4 ± 47.09e | 12.2 ± 1.42 |
HTHXFZ | 502.4 ± 122.0e | 246.9 ± 22.2e | 12.4 ± 1.05 |
M | 720.6 ± 136.14e | 252.9 ± 30.8e | 11.4 ± 0.89d |
HTHXFZH |
引文著录: 林唐唐, 郑保平, 刘海华, 唐杨, 肖海, 韩立民. 化痰活血扶正方及其拆方后的相关药组对模型大鼠肝纤维化指标的影响. 世界华人消化杂志 2018; 26(18): 1095-1101