临床研究
Copyright ©The Author(s) 2016.
世界华人消化杂志. 2016-05-08; 24(13): 1976-1983
在线出版 2016-05-08. doi: 10.11569/wcjd.v24.i13.1976
表1 胃癌组与慢性胃炎组之间差异有统计学意义的蛋白质峰
序号m/z胃癌组(mean±SD)胃炎组(mean±SD)胃癌/胃炎胃炎/胃癌P胃癌组表达上调/下调
14267.0983.582±4.28315.647±11.5370.2294.3680.000Down
22135.4052.830±2.7206.398±3.9230.4422.2610.000Down
32606.8281.364±1.5384.078±3.7630.3342.9900.000Down
46564.8573.180±3.3340.950±1.6953.3450.2990.000Up
5 13053.090 0.892±1.096 0.245±0.504 3.645 0.274 0.000 Up
6 5438.674 3.591±3.827 1.736±2.425 2.069 0.483 0.000 Up
7 2912.397 10.019±12.771 2.980±2.681 3.362 0.297 0.001 Up
8 12566.820 0.722±0.810 0.193±0.301 3.737 0.268 0.001 Up
9 2957.555 5.646±5.465 2.217±2.940 2.546 0.393 0.001 Up
10 6294.777 3.305±3.464 1.016±1.694 3.255 0.307 0.002 Up
11 3619.969 4.391±4.535 1.737±1.316 2.528 0.396 0.002 Up
12 6523.113 5.030±5.651 1.520±2.762 3.309 0.302 0.004 Up
13 5369.372 6.567±7.468 3.186±6.010 2.061 0.485 0.004 Up
14 3872.659 1.770±1.557 0.733±1.128 2.416 0.414 0.005 Up
1510733.2802.017±2.4930.879±2.3062.2950.4360.006Up
162217.5865.424±11.10211.909±20.0740.4552.1950.007Down
172979.6712.543±2.3461.111±1.6252.2890.4370.007Up
182127.5840.486±1.8181.553±2.1070.3133.1940.013Down
192084.8881.519±2.7070.179±1.3268.4700.1180.022Up
202945.2063.143±4.0871.324±1.5262.3740.4210.026Up
212330.6241.417±1.8230.391±1.2743.6210.2760.027Up
223677.9402.576±3.3870.980±1.0902.6280.3810.030Up
232265.5651.682±2.3440.475±1.1613.5390.2830.040Up
表2 所建诊断模型对胃癌的诊断效率(临床回代检验结果)
分组n正确诊断错误诊断正确率(%)
胃癌组 57 55 2 96
慢性胃炎组 28 24 4 86
表3 所建诊断模型对胃癌的诊断效率(十字交叉验证结果)
分组n正确诊断错误诊断正确率(%)
胃癌组 57 51 6 89
慢性胃炎组 28 21 7 75

引文著录: 谢梦洲, 贺佐梅, 黄飞娟, 周小青, 吴正治. 胃癌与慢性胃炎的唾液蛋白指纹图谱鉴别诊断模型. 世界华人消化杂志 2016; 24(13): 1976-1983