慢性乙型肝炎患者外周血T细胞标记物表达及细胞因子水平与中医分型的关系

表1 中医分型各组在慢性乙型肝炎轻、中、重三型中所占比例

	慢乙肝轻度(%)	慢乙肝中度(%)	慢乙肝重度(%)
肝郁脾虚	27(55.1%)	18(36.7%)	4(8.2%)
湿热中阻	10(40.0%)	9(36.0%)	6(24.0%)
肝肾阴虚	7(32.0%)	9(41.0%)	6(27.0%)
瘀血阻络	5(19.0%)	9(35.0%)	12(46.0%)
脾肾阳虚	1(50.0%)	1(50.0%)	0(0%)

表2 正常人与慢性乙肝患者的CD28在中医辨证分型组中的表达情况(%)

组别	n	CD28+ CD4+	CD28+CD8+	CD4/CD8
肝郁脾虚	49	34.42±8.70df	21.62±7.66	1.08±0.51d
湿热中阻	25	33.51±9.47de	25.39±7.27bd	1.01±0.41d
肝肾阴虚	22	40.83±6.59a	18.65±7.50	1.47±0.57
瘀血阻络	26	25.56±12.75ad	24.40±7.00	0.81±0.53d
正常对照组	20	34.09±4.70	19.20±4.14	1.16±0.28

^aP<0.05,

^bP<0.01 vs 正常对照组;

^dP<0.01 vs 肝肾阴虚组;

^eP<0.05, fP<0.01 vs 瘀血阻络组.

表3 各组患者血清IL-2、IL-10、IL-12和IFN-γ水平(mean±SD, ng/L).

组别	n	IL-2	IL-10	IL-12	IFN-g
肝郁脾虚	49	38.44±20.92a	15.70±8.81b	38.72±13.71a	20.07±22.06
湿热中阻	25	35.90±9.13a	15.19±8.64a	54.21±13.38a	21.71±13.90
肝肾阴虚	22	25.79±15.81	11.81±4.67	28.02±20.77	34.75±27.71b
瘀血阻络	26	24.17±8.71	12.66±16.10	26.34±19.99	31.72±29.80b
正常对照	20	25.38±3.80	8.43±4.55	24.08±15.50	16.28±22.20

^aP<0.05,

^bP<0.01 vs 正常对照.