Refinement of heterozygosity loss on chromosome 5p15 in sporadic colorectal cancer

Table 1 The ratios of LOH of all loci on chromosome 5

Loci	Map location	Number of informative cases (%)	LOH No (%)
D5S1981	p15.3	24 (28.92)	3 (12.50)
D5S406	p15.3	26 (31.33)	5 (19.23)
D5S630	p15.3	65 (78.31)	8 (12.31)
D5S416	p15.2	54 (65.06)	26 (48.15)
D5S419	p13.3	63 (75.90)	7 (11.11)
D5S418	p13.1	66 (79.52)	15 (22.73)
D5S407	q11.2	51 (61.45)	10 (19.61)
D5S647	q12.2	74 (89.16)	16 (21.62)
D5S424	q13.2	36 (43.37)	8 (22.22)
D5S428	q14.1	61 (73.49)	23 (37.70)
D5S2027	q21.1	46 (55.42)	15 (32.61)
D5S471	q23.1	62 (74.70)	24 (38.71)
D5S2115	q31.1	59 (71.08)	19 (32.20)
D5S410	q33.2	18 (21.69)	8 (44.44)
D5S400	q35.1	28 (33.73)	4 (14.39)
D5S408	q35.3	61 (73.49)	6 (9.84)

Table 2 The ratios of LOH of the loci on 5p15 region

Loci	Map location	Space of two loci (cM)	Number of Informative cases (%)	LOH No (%)
D5S630	p15.3	2.2	65 (78.31)	8 (12.31)
D5S1987	p15.3	4.7	67 (80.31)	11 (16.42)
D5S1991	p15.3	0.6	50 (60.24)	6 (12.00)
D5S1954	p15.3	0.1	48 (57.83)	16 (33.33)
D5S1963	p15.2	0.8	57 (68.67)	12 (21.05)
D5S416	p15.2	1.0	54 (65.06)	26 (48.15)
D5S2114	p15.2	2.2	53 (63.86)	7 (13.21)
D5S486	p15.1		60 (72.29)	10 (16.67)