Fatty metamorphosis of the liver in patients with breast cancer: Possible associated factors

Table 1 Clinical variables in patients with breast cancer and controls

Variables	Cases (n = 217)Number (%)	Controls (n = 182)Number (%)	P
Fatty liver
No	119 (54.8)	145 (79.7)
Yes	98 (45.2)	37 (20.3)	< 0.0001
Overweight
No	93 (42.9)	137 (75.3)
Yes	124 (57.1)	45 (24.7)	< 0.0001
Hyperlipidemia
No	177 (81.6)	154 (84.6)
Yes	40 (18.4)	28 (15.4)	0.432
Hepatitis C
No	204 (94.0)	165 (90.6)
Yes	13 (6.0)	17 (9.4)	0.144
Age
Mean ± SD	48.6 ± 10.5	46.8 ± 12.0	0.029

Table 2 Clinical factors associated with fatty liver in patients with breast cancer (n = 217)

Variables	Number of cases		P
	Fatty Liver (-)	Fatty Liver (+)
Contraceptives
No	117	94
Yes	2	4	0.28
Tamoxifen
No	25	13
Yes	94	85	0.14
Chemotherapy
No	52	49
Yes	58	47	0.59
Hepatitis C
No	116	88
Yes	10	3	0.031
Diabetes
No	113	92
Yes	6	6	0.73
Overweight
No	71	21
Yes	48	77	< 0.0001
Hyperlipidemia
No	106	71
Yes	13	27	0.017

Table 3 Significant variables on multivariate analysis for patients with breast cancer

Variables	Coefficient estimates and significant test
	Coefficient	SD	P	Odds ratio
Overweight	0.3410	0.0474	0.0000	1.406 4
Hyperlipidemia	0.0263	0.0132	0.0473	1.2066